Concepedia

Synaptic Scaling

Synaptic Scaling is a form of homeostatic synaptic plasticity in which an individual neuron, in response to sustained changes in its own activity, multiplicatively adjusts the strength of all its excitatory synapses by globally up- or down-regulating postsynaptic receptor efficacy so as to stabilize its average firing rate while preserving relative synaptic weights.

205

Publications

22.8K

Citations

719

Authors

304

Institutions

Publications per year

2017–2026

67

Parents

Children

Publications

205

Activity-dependent scaling of quantal amplitude in neocortical neurons

Gina G. Turrigiano, Kenneth R. Leslie, Niraj S. Desai et al. · Nature · 1998 · 2.3K citations

, , +16

Synaptic scaling mediated by glial TNF-α

David Stellwagen, Robert C. Malenka · Nature · 2006 · 1.7K citations

, , +14

Arc/Arg3.1 Mediates Homeostatic Synaptic Scaling of AMPA Receptors

Jason D. Shepherd, Gavin Rumbaugh, Jing Wu et al. · Neuron · 2006 · 795 citations · Full text

, , +14

Stable Hebbian Learning from Spike Timing-Dependent Plasticity

Mark C. W. van Rossum, Guo‐Qiang Bi, Gina G. Turrigiano · Journal of Neuroscience · 2000 · 740 citations · Full text

, , +15

Critical periods for experience-dependent synaptic scaling in visual cortex

Niraj S. Desai, Robert H. Cudmore, Sacha B. Nelson et al. · Nature Neuroscience · 2002 · 606 citations

, , +16

1–5 of 205

Authors

719

  1. GG
    Gina G. Turrigiano

    Brandeis University, United States

    18 publications · 6.2K citations

    18

    h-index

  2. PW
    Peter Wenner

    Emory University, United States

    6 publications · 257 citations

    6

    h-index

  3. CT
    Christian Tetzlaff

    University of Göttingen, Germany

    6 publications · 320 citations

    6

    h-index

  4. RL
    Richard L. Huganir

    Johns Hopkins University, United States

    6 publications · 1.8K citations

    6

    h-index

  5. NZ
    Noam Ziv

    Rappaport Family Institute for Research in the Medical Sciences, Israel

    5 publications · 405 citations

    5

    h-index

1–5 of 719

Institutions

304

  1. Brandeis University

    Waltham, United States

    21 h-index

    75 publications

    24.7K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    28 publications

    5.4K citations

  3. Johns Hopkins University

    Baltimore, United States

    10 h-index

    48 publications

    12.4K citations

  4. University of California San Diego

    San Diego, United States

    9 h-index

    18 publications

    4K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    32 publications

    1.6K citations

  6. Johns Hopkins Medicine

    Baltimore, United States

    7 h-index

    29 publications

    8.8K citations

  7. University of Göttingen

    Göttingen, Germany

    7 h-index

    18 publications

    735 citations

  8. Emory University

    Atlanta, United States

    6 h-index

    20 publications

    731 citations

1–8 of 304

Venues

  1. Journal of Neuroscience

    32 publications · 3.9K citations

    28

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 1.1K citations

    10

    h-index

  3. Neuron

    10 publications · 3.2K citations

    10

    h-index

  4. PLoS Computational Biology

    9 publications · 388 citations

    9

    h-index

  5. eLife

    6 publications · 302 citations

    6

    h-index

1–5