Concepedia

Substrate Strain Effects

Substrate Strain Effects is a mechanistic concept in enzyme catalysis wherein the distortion or strain induced in the substrate upon binding to the enzyme selectively stabilizes the transition state by preferentially weakening bonds or altering geometry, thereby lowering the activation energy required for the reaction.

149

Publications

9.3K

Citations

737

Authors

300

Institutions

Publications per year

2017–2026

26

Parents

Publications

149

Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain

Ichiro Owan, David B. Burr, Charles H. Turner et al. · American Journal of Physiology-Cell Physiology · 1997 · 467 citations

, , +17

Effect of Substrate Strain on Adsorption

M. Gsell, P. Jakob, D. Menzel · Science · 1998 · 394 citations

, , +17

Substrate Deformation Levels Associated With Routine Physical Activity Are Less Stimulatory to Bone Cells Relative to Loading-Induced Oscillatory Fluid Flow

J. You, Clare E. Yellowley, Henry J. Donahue et al. · Journal of Biomechanical Engineering · 2000 · 359 citations

, , +17

Surface Strain versus Substrate Interaction in Heteroepitaxial Metal Layers: Pt on Ru(0001)

A. Schlapka, Markus Lischka, Axel Groß et al. · Physical Review Letters · 2003 · 355 citations

, , +17

Strain-Induced Self Organization of Metal−Insulator Domains in Single-Crystalline VO<sub>2</sub> Nanobeams

Junqiao Wu, Qian Gu, Beth S. Guiton et al. · Nano Letters · 2006 · 307 citations

, , +16

1–5 of 149

Authors

737

  1. TV
    T. Venkatesan

    University of Maryland, College Park, United States

    3 publications · 137 citations

    3

    h-index

  2. LC
    Long‐Qing Chen

    Pennsylvania State University, United States

    3 publications · 78 citations

    3

    h-index

  3. FZ
    Feng Zhai

    Zhejiang Normal University, China

    3 publications · 234 citations

    3

    h-index

  4. AB
    Amlan Biswas

    University of Florida, United States

    3 publications · 216 citations

    3

    h-index

  5. MR
    M. Rajeswari

    University of Maryland, College Park, United States

    2 publications · 117 citations

    2

    h-index

1–5 of 737

Institutions

300

  1. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    25 publications

    2.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    33 publications

    897 citations

  3. Pennsylvania State University

    State College, United States

    6 h-index

    20 publications

    2.8K citations

  4. Institute of Physics

    Beijing, China

    6 h-index

    25 publications

    1.7K citations

  5. Brookhaven National Laboratory

    Upton, United States

    5 h-index

    11 publications

    933 citations

  6. National University of Singapore

    Singapore, Singapore

    4 h-index

    29 publications

    1.6K citations

  7. University of Oxford

    Oxford, United Kingdom

    4 h-index

    9 publications

    207 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    16 publications

    2.1K citations

1–8 of 300

Venues

  1. Applied Physics Letters

    29 publications · 1.7K citations

    21

    h-index

  2. Journal of Applied Physics

    15 publications · 569 citations

    12

    h-index

  3. Physical Review B

    PRB · 5 publications · 335 citations

    5

    h-index

  4. Physical Review Letters

    PRL · 5 publications · 466 citations

    5

    h-index

  5. Nano Letters

    4 publications · 592 citations

    4

    h-index

1–5