Concepedia

Substrate Channeling Orientation

Substrate Channeling Orientation is an organizational principle in metabolic engineering that directs the spatial arrangement of enzymes to facilitate the direct transfer of intermediates between active sites, thereby minimizing diffusion and enhancing catalytic efficiency.

35

Publications

1.5K

Citations

142

Authors

67

Institutions

Publications per year

2017–2026

7

Parents

Publications

35

Directional Regulation of Enzyme Pathways through the Control of Substrate Channeling on a DNA Origami Scaffold

Guoliang Ke, Minghui Liu, Shuoxing Jiang et al. · Angewandte Chemie International Edition · 2016 · 150 citations

, , +17

A Synthetic Light-Driven Substrate Channeling System for Precise Regulation of Enzyme Cascade Activity Based on DNA Origami

Yahong Chen, Guoliang Ke, Yanli Ma et al. · Journal of the American Chemical Society · 2018 · 140 citations

, , +16

Organization of the terminal two enzymes of the heme biosynthetic pathway. Orientation of protoporphyrinogen oxidase and evidence for a membrane complex.

Glória C. Ferreira, T. L. Andrew, Susan W. Karr et al. · Journal of Biological Chemistry · 1988 · 121 citations · Full text

, , +17

Metabolon Catalyzed Pyruvate/Air Biofuel Cell

Michael J. Moehlenbrock, Timothy K. Toby, Abdul Waheed et al. · Journal of the American Chemical Society · 2010 · 97 citations · Full text

, , +17

Cross-Talk and Ammonia Channeling between Active Centers in the Unexpected Domain Arrangement of Glutamate Synthase

Claudia Binda, R Bossi, Soichi Wakatsuki et al. · Structure · 2000 · 86 citations · Full text

, , +6

1–5 of 35

Authors

142

  1. HY
    Hao Yan

    Arizona State University, United States

    3 publications · 314 citations

    3

    h-index

  2. ML
    Minghui Liu

    Arizona State University, United States

    3 publications · 314 citations

    3

    h-index

  3. ZZ
    Zhi Zhu

    Xiamen University, China

    3 publications · 314 citations

    3

    h-index

  4. GK
    Guoliang Ke

    Hunan University, China

    3 publications · 314 citations

    3

    h-index

  5. YL
    Yan Liu

    Arizona State University, United States

    3 publications · 314 citations

    3

    h-index

1–5 of 142

Institutions

67

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    15 publications

    341 citations

  2. Collaborative Innovation Center of Chemistry for Energy Materials

    Shanghai, China

    3 h-index

    10 publications

    1.1K citations

  3. Arizona State University

    Tempe, United States

    3 h-index

    21 publications

    2K citations

  4. Xiamen University

    Xiamen, China

    3 h-index

    10 publications

    1.1K citations

  5. University of Nebraska–Lincoln

    Lincoln, United States

    2 h-index

    7 publications

    270 citations

  6. University of Georgia

    Athens, United States

    2 h-index

    7 publications

    622 citations

  7. Yale University

    New Haven, United States

    2 h-index

    7 publications

    298 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    9 publications

    332 citations

1–8 of 67

Venues

  1. Journal of Biological Chemistry

    JBC · 5 publications · 268 citations

    5

    h-index

  2. Journal of Molecular Biology

    JMB · 4 publications · 122 citations

    4

    h-index

  3. Biochemistry

    3 publications · 115 citations

    3

    h-index

  4. Journal of Theoretical Biology

    2 publications · 37 citations

    2

    h-index

  5. Journal of the American Chemical Society

    JACS · 2 publications · 237 citations

    2

    h-index

1–5