Concepedia

Subgroup Efficacy Analysis

Subgroup Efficacy Analysis is a statistical method used in clinical trial evaluation that assesses the effectiveness of a drug within specific subpopulations of patients defined by particular characteristics, thereby identifying differential treatment effects across subgroups while maintaining rigorous control for multiplicity and bias.

65

Publications

3.6K

Citations

631

Authors

325

Institutions

Publications per year

2017–2026

25

Parents

Publications

65

Testing for Qualitative Interactions between Treatment Effects and Patient Subsets

Mitchell H. Gail, Richard Simon · Biometrics · 1985 · 655 citations

, , +15

A Critical Appraisal of the Reporting of the National Acute Spinal Cord Injury Studies (II and III) of Methylprednisolone in Acute Spinal Cord Injury

William P. Coleman, Edward Benzel, David W. Cahill et al. · Journal of Spinal Disorders · 2000 · 294 citations

, , +13

Acarbose Slows Progression of Intima-Media Thickness of the Carotid Arteries in Subjects With Impaired Glucose Tolerance

M Hanefeld, Jean Louis Chiasson, Carsta Koehler et al. · Stroke · 2004 · 254 citations · Full text

, , +17

Patient subsets and variation in therapeutic efficacy.

Richard Simon · British Journal of Clinical Pharmacology · 1982 · 132 citations · Full text

, , +15

Effect of Oral Digoxin in High-Risk Heart Failure Patients: A Pre-Specified Subgroup Analysis of the DIG Trial

Mihai Gheorghiade, Kanan Patel, Gerasimos Filippatos et al. · European Journal of Heart Failure · 2013 · 110 citations · Full text

, , +14

1–5 of 65

Authors

631

  1. MF
    Mohammad F. Huque

    Office of Science, United States

    3 publications · 163 citations

    3

    h-index

  2. MA
    Mohamed Alosh

    King Saud University, Saudi Arabia

    3 publications · 163 citations

    3

    h-index

  3. CS
    Constantine S. Tam

    Peter MacCallum Cancer Centre, Australia

    2 publications · 48 citations

    2

    h-index

  4. YD
    Ying Ding

    University of Pittsburgh, United States

    2 publications · 46 citations

    2

    h-index

  5. RS
    Richard Simon

    National Cancer Institute, United States

    2 publications · 787 citations

    2

    h-index

1–5 of 631

Institutions

325

  1. The Ohio State University

    Columbus, United States

    5 h-index

    6 publications

    130 citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    4 h-index

    7 publications

    193 citations

  3. Eli Lilly (United States)

    Indianapolis, United States

    4 h-index

    8 publications

    172 citations

  4. Novartis (Switzerland)

    Basel, Switzerland

    4 h-index

    13 publications

    784 citations

  5. University Medical Center Utrecht

    Utrecht, The Netherlands

    3 h-index

    5 publications

    129 citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    7 publications

    281 citations

  7. Cornell University

    Ithaca, United States

    3 h-index

    3 publications

    171 citations

  8. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    4 publications

    85 citations

1–8 of 325

Venues

  1. Statistics in Medicine

    7 publications · 379 citations

    7

    h-index

  2. Journal of Clinical Oncology

    3 publications · 44 citations

    3

    h-index

  3. Biometrics

    2 publications · 687 citations

    2

    h-index

  4. Statistics in Biopharmaceutical Research

    SBR · 2 publications · 106 citations

    2

    h-index

  5. Statistical Methods in Medical Research

    2 publications · 63 citations

    2

    h-index

1–5