Concepedia

Subclonal Mutation Detection

Subclonal Mutation Detection is a computational method in cancer genomics that identifies mutations present in only a subset of tumor cells, distinguishing it from clonal mutation detection by resolving genetic heterogeneity within tumors at the subpopulation level.

24

Publications

3.7K

Citations

297

Authors

108

Institutions

Publications per year

2017–2026

9

Parents

Publications

24

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

Jianjun Zhang, Junya Fujimoto, Jianhua Zhang et al. · Science · 2014 · 1K citations

, , +17

SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution

Christopher A. Miller, Brian S. White, Nathan D. Dees et al. · PLoS Computational Biology · 2014 · 495 citations · Full text

, , +17

MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data

Yu Fan, Xi Liu, Daniel Hughes et al. · Genome biology · 2016 · 310 citations · Full text

, , +17

Intra- and Inter-Tumor Heterogeneity of BRAFV600EMutations in Primary and Metastatic Melanoma

Molly Yancovitz, Adam J. Litterman, Joanne Yoon et al. · PLoS ONE · 2012 · 286 citations · Full text

, , +17

Reliable detection of subclonal single-nucleotide variants in tumour cell populations

Moritz Gerstung, Christian Beisel, Markus Rechsteiner et al. · Nature Communications · 2012 · 258 citations · Full text

, , +16

1–5 of 24

Authors

297

  1. JZ
    Jianjun Zhang

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 1.3K citations

    2

    h-index

  2. TJ
    Timothy J. Ley

    Washington University in St. Louis, United States

    2 publications · 584 citations

    2

    h-index

  3. HM
    Holger Moch

    University Hospital of Zurich, Switzerland

    2 publications · 269 citations

    2

    h-index

  4. ND
    Nathan D. Dees

    Washington University in St. Louis, United States

    2 publications · 584 citations

    2

    h-index

  5. CA
    Christopher A. Miller

    Washington University in St. Louis, United States

    2 publications · 584 citations

    2

    h-index

1–5 of 297

Institutions

108

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    31 publications

    27.8K citations

  2. Wellcome Sanger Institute

    Cambridge, United Kingdom

    2 h-index

    5 publications

    2.5K citations

  3. Washington University in St. Louis

    St Louis, United States

    2 h-index

    31 publications

    9.3K citations

  4. University of Zurich

    Zurich, Switzerland

    2 h-index

    7 publications

    1.1K citations

  5. University Hospital of Zurich

    Zurich, Switzerland

    2 h-index

    7 publications

    1.1K citations

  6. ETH Zurich

    Zurich, Switzerland

    2 h-index

    10 publications

    851 citations

  7. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    2 h-index

    6 publications

    313 citations

  8. Hôpital Robert-Debré

    Paris, France

    1 h-index

    1 publications

    162 citations

1–8 of 108

Venues

  1. Nature Communications

    2 publications · 337 citations

    2

    h-index

  2. Genome biology

    2 publications · 411 citations

    2

    h-index

  3. Clinical Cancer Research

    2 publications · 258 citations

    2

    h-index

  4. Blood

    2 publications · 53 citations

    2

    h-index

  5. PLoS ONE

    2 publications · 375 citations

    2

    h-index

1–5