Concepedia

Strychnine Biosynthesis

Strychnine Biosynthesis is a specialized metabolic pathway within alkaloid biosynthesis that entails the enzymatic formation of strychnine, a complex monoterpene indole alkaloid, from primary metabolites in plants of the genus *Strychnos*, distinguished by its unique sequence of cyclization and rearrangement reactions leading to the characteristic heptacyclic scaffold.

56

Publications

2.3K

Citations

160

Authors

48

Institutions

Publications per year

2017–2026

3

Parents

Publications

56

Biosynthesis of strychnine

Benke Hong, Dagny Grzech, Lorenzo Caputi et al. · Nature · 2022 · 165 citations · Full text

, , +10

Biogenetically Inspired Approach to the <i>Strychnos </i>Alkaloids. Concise Syntheses of (±)-Akuammicine and (±)-Strychnine

Masayuki Ito, Cameron W. Clark, Michael Mortimore et al. · Journal of the American Chemical Society · 2001 · 159 citations

, , +14

Unlocking the Diversity of Alkaloids in Catharanthus roseus: Nuclear Localization Suggests Metabolic Channeling in Secondary Metabolism

Anna K Stavrinides, Evangelos C. Tatsis, Emilien Foureau et al. · Chemistry & Biology · 2015 · 127 citations · Full text

, , +17

Efficient Access to the Core of the <i>Strychnos</i>, <i>Aspidosperma</i> and <i>Iboga</i> Alkaloids. A Short Synthesis of Norfluorocurarine

David B. C. Martin, Christopher D. Vanderwal · Journal of the American Chemical Society · 2009 · 115 citations

, , +10

Purine and purine alkaloid metabolism in Camellia and Coffea plants

Takeo Suzuki, Hiroshi Ashihara, George R. Waller · Phytochemistry · 1992 · 110 citations

, , +11

1–5 of 56

Authors

160

  1. NB
    N.G. Bisset

    Queen Charlotte's and Chelsea Hospital, United Kingdom

    4 publications · 54 citations

    4

    h-index

  2. ME
    Martin E. Kuehne

    University of Vermont, United States

    4 publications · 122 citations

    4

    h-index

  3. JB
    Joan Bosch

    Universitat de Barcelona, Spain

    3 publications · 92 citations

    3

    h-index

  4. NV
    Nigel Vicker

    University of Bath, United Kingdom

    3 publications · 251 citations

    3

    h-index

  5. DB
    Dan Bougie

    Iowa State University, United States

    3 publications · 67 citations

    3

    h-index

1–5 of 160

Institutions

48

  1. Queen Charlotte's and Chelsea Hospital

    London, United Kingdom

    3 h-index

    7 publications

    87 citations

  2. University of Vermont

    Burlington, United States

    3 h-index

    8 publications

    188 citations

  3. Istituto Superiore di Sanità

    Rome, Italy

    2 h-index

    6 publications

    70 citations

  4. Iowa State University

    Ames, United States

    2 h-index

    4 publications

    60 citations

  5. Universitat de Barcelona

    Barcelona, Spain

    2 h-index

    10 publications

    228 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    7 publications

    213 citations

  7. University of Liège

    Liège, Belgium

    2 h-index

    4 publications

    85 citations

  8. Institut de Chimie des Substances Naturelles

    Gif-sur-Yvette, France

    2 h-index

    4 publications

    80 citations

1–8 of 48

Venues

  1. Journal of the American Chemical Society

    JACS · 9 publications · 646 citations

    9

    h-index

  2. Tetrahedron

    6 publications · 156 citations

    6

    h-index

  3. Tetrahedron Letters

    6 publications · 189 citations

    6

    h-index

  4. Phytochemistry

    5 publications · 178 citations

    5

    h-index

  5. The Journal of Organic Chemistry

    JOC · 4 publications · 216 citations

    4

    h-index

1–5