Concepedia

Structure-based Pharmacophore Mapping

Structure-Based Pharmacophore Mapping is a computational method in drug design that derives a pharmacophore model by analyzing the three-dimensional structure of a target protein, distinguishing it from ligand-based approaches through its reliance on protein-ligand interaction features rather than ligand similarity.

124

Publications

5.8K

Citations

652

Authors

219

Institutions

Publications per year

2017–2026

35

Parents

Publications

124

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach

Xiaofeng Liu, Sisheng Ouyang, Biao Yu et al. · Nucleic Acids Research · 2010 · 947 citations · Full text

, , +17

A fast new approach to pharmacophore mapping and its application to dopaminergic and benzodiazepine agonists

Yvonne C. Martin, Mark G. Bures, Elizabeth A. Danaher et al. · Journal of Computer-Aided Molecular Design · 1993 · 405 citations

, , +12

Structure based pharmacophore modeling, virtual screening, molecular docking and ADMET approaches for identification of natural anti-cancer agents targeting XIAP protein

F A Dain Md Opo, Mohammed M. Rahman, Foysal Ahammad et al. · Scientific Reports · 2021 · 295 citations · Full text

, , +17

Acetylcholinesterase Inhibitory Activity of Scopolin and Scopoletin Discovered by Virtual Screening of Natural Products

Judith M. Rollinger, Ariane Hornick, Thierry Langer et al. · Journal of Medicinal Chemistry · 2004 · 209 citations · Full text

, , +17

ALADDIN: An integrated tool for computer-assisted molecular design and pharmacophore recognition from geometric, steric, and substructure searching of three-dimensional molecular structures

John H. Van Drie, David Weininger, Yvonne C. Martin · Journal of Computer-Aided Molecular Design · 1989 · 189 citations

, , +16

1–5 of 124

Authors

652

  1. TJ
    Tarun Jha

    Jadavpur University, India

    5 publications · 140 citations

    5

    h-index

  2. CG
    Christian Griesinger

    Max Planck Institute for Biophysical Chemistry, Germany

    4 publications · 287 citations

    4

    h-index

  3. TC
    Teresa Carlomagno

    Max Planck Institute for Biophysical Chemistry, Germany

    3 publications · 270 citations

    3

    h-index

  4. NA
    Nilanjan Adhikari

    Jadavpur University, India

    3 publications · 86 citations

    3

    h-index

  5. SS
    Shalini Saxena

    Birla Institute of Technology and Science, Pilani, India

    3 publications · 93 citations

    3

    h-index

1–5 of 652

Institutions

219

  1. Jadavpur University

    Kolkata, India

    6 h-index

    17 publications

    407 citations

  2. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    4 h-index

    12 publications

    1K citations

  3. Dr. Hari Singh Gour University

    Saugor, India

    3 h-index

    6 publications

    162 citations

  4. University of Jordan

    Amman, Jordan

    3 h-index

    7 publications

    246 citations

  5. Gyeongsang National University

    Jinju-si, South Korea

    3 h-index

    10 publications

    552 citations

  6. China Pharmaceutical University

    Nanjing, China

    3 h-index

    9 publications

    305 citations

  7. Universidade de São Paulo

    São Paulo, Brazil

    3 h-index

    9 publications

    286 citations

  8. University of Hyderabad

    Hyderabad, India

    3 h-index

    7 publications

    243 citations

1–8 of 219

Venues

  1. Journal of Biomolecular Structure and Dynamics

    12 publications · 322 citations

    12

    h-index

  2. Journal of Medicinal Chemistry

    10 publications · 843 citations

    10

    h-index

  3. Journal of Chemical Information and Modeling

    JCIM · 11 publications · 285 citations

    10

    h-index

  4. Journal of Computer-Aided Molecular Design

    8 publications · 884 citations

    8

    h-index

  5. European Journal of Medicinal Chemistry

    8 publications · 312 citations

    8

    h-index

1–5