Concepedia

Structure-based Pharmacophore Alignment

Structure-Based Pharmacophore Alignment is a computational method in drug discovery that derives and aligns pharmacophore features directly from the three-dimensional structures of target-ligand complexes to identify spatially and chemically congruent interaction points essential for molecular recognition.

67

Publications

2.2K

Citations

382

Authors

135

Institutions

Publications per year

2017–2026

8

Parents

Publications

67

Novel Approach for Efficient Pharmacophore-Based Virtual Screening: Method and Applications

Oranit Dror, Dina Schneidman‐Duhovny, Yuval Inbar et al. · Journal of Chemical Information and Modeling · 2009 · 140 citations · Full text

, , +12

Quantitative Structure−Activity Relationships for γδ T Cell Activation by Bisphosphonates

John M. Sanders, Subhash Chandra Ghosh, Julian M. W. Chan et al. · Journal of Medicinal Chemistry · 2003 · 114 citations

, , +17

Pharmacophore-Based discovery of substituted pyridines as novel dopamine transporter inhibitors

Istvan Enyedy, Sukumar Sakamuri, Wahiduz A. Zaman et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 87 citations · Full text

, , +16

Consensus Superiority of the Pharmacophore-Based Alignment, Over Maximum Common Substructure (MCS): 3D-QSAR Studies on Carbamates as Acetylcholinesterase Inhibitors

Shailendra S. Chaudhaery, Kuldeep K. Roy, Anil K. Saxena · Journal of Chemical Information and Modeling · 2009 · 55 citations

, , +14

Flexible matching of test ligands to a 3D pharmacophore using a molecular superposition force field: Comparison of predicted and experimental conformations of inhibitors of three enzymes

Colin McMartin, Regine S. Bohacek · Journal of Computer-Aided Molecular Design · 1995 · 55 citations

, , +17

1–5 of 67

Authors

382

  1. AD
    Adriano D. Andricopulo

    Universidade de São Paulo, Brazil

    3 publications · 108 citations

    3

    h-index

  2. WA
    Wahiduz A. Zaman

    The University of Texas Medical Branch at Galveston, United States

    2 publications · 136 citations

    2

    h-index

  3. ZU
    Zaheer Ul‐Haq

    University of Karachi, Pakistan

    2 publications · 32 citations

    2

    h-index

  4. KM
    Kenneth M. Johnson

    The University of Texas Medical Branch at Galveston, United States

    2 publications · 136 citations

    2

    h-index

  5. FW
    Fengbo Wu

    Sichuan University, China

    2 publications · 35 citations

    2

    h-index

1–5 of 382

Institutions

135

  1. Universidade de São Paulo

    São Paulo, Brazil

    3 h-index

    9 publications

    384 citations

  2. China Pharmaceutical University

    Nanjing, China

    3 h-index

    17 publications

    515 citations

  3. University of Siena

    Siena, Italy

    2 h-index

    12 publications

    260 citations

  4. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    6 publications

    112 citations

  5. The University of Texas Medical Branch at Galveston

    Galveston, United States

    2 h-index

    4 publications

    272 citations

  6. Kunming Institute of Botany

    Kunming, China

    2 h-index

    6 publications

    112 citations

  7. International Center for Chemical and Biological Sciences

    Karachi, Pakistan

    2 h-index

    4 publications

    64 citations

  8. Pfizer (United States)

    New York, United States

    2 h-index

    18 publications

    528 citations

1–8 of 135

Venues

  1. Bioorganic & Medicinal Chemistry Letters

    10 publications · 358 citations

    10

    h-index

  2. Journal of Chemical Information and Modeling

    JCIM · 9 publications · 388 citations

    9

    h-index

  3. Bioorganic & Medicinal Chemistry

    6 publications · 195 citations

    6

    h-index

  4. European Journal of Medicinal Chemistry

    5 publications · 185 citations

    5

    h-index

  5. Journal of Molecular Graphics and Modelling

    6 publications · 159 citations

    5

    h-index

1–5