Concepedia

Structural Basis Of Fidelity

Structural Basis of Fidelity is a theoretical framework in molecular biology that elucidates the precise three-dimensional architectural features of RNA polymerase responsible for ensuring accurate nucleotide selection and incorporation during transcription.

91

Publications

5.7K

Citations

303

Authors

110

Institutions

Publications per year

2017–2026

11

Parents

Publications

91

Crystal Structures of Human DNA Polymerase β Complexed with DNA:  Implications for Catalytic Mechanism, Processivity, and Fidelity<sup>,</sup>

H. Pelletier, M.R. Sawaya, William T. Wolfle et al. · Biochemistry · 1996 · 251 citations

, , +17

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ

M.K. Swan, Robert E. Johnson, Louise Prakash et al. · Nature Structural & Molecular Biology · 2009 · 251 citations · Full text

, , +15

Architecture of the RNA polymerase–Spt4/5 complex and basis of universal transcription processivity

Fuensanta W. Martínez-Rucobo, Sarah Sainsbury, Alan C. M. Cheung et al. · The EMBO Journal · 2011 · 237 citations · Full text

, , +14

Structural basis for the dual coding potential of 8‐oxoguanosine by a high‐fidelity DNA polymerase

Luis G. Brieba, Brandt F. Eichman, Robert J. Kokoska et al. · The EMBO Journal · 2004 · 210 citations · Full text

, , +13

A single side chain prevents <i>Escherichia coli</i> DNA polymerase I (Klenow fragment) from incorporating ribonucleotides

Mekbib Astatke, Kimmie Ng, Nigel D. F. Grindley et al. · Proceedings of the National Academy of Sciences · 1998 · 207 citations · Full text

, , +17

1–5 of 91

Authors

303

  1. SH
    Samuel H. Wilson

    National Institutes of Health, United States

    12 publications · 1K citations

    12

    h-index

  2. WA
    William A. Beard

    National Institute of Environmental Health Sciences, United States

    10 publications · 769 citations

    10

    h-index

  3. JJ
    Jamie J. Arnold

    Pennsylvania State University, United States

    6 publications · 407 citations

    6

    h-index

  4. CE
    Craig E. Cameron

    Pennsylvania State University, United States

    6 publications · 408 citations

    6

    h-index

  5. TA
    Thomas A. Kunkel

    National Institute of Environmental Health Sciences, United States

    6 publications · 573 citations

    6

    h-index

1–5 of 303

Institutions

110

  1. National Institute of Environmental Health Sciences

    Durham, United States

    14 h-index

    49 publications

    3.8K citations

  2. National Institutes of Health

    Bethesda, United States

    11 h-index

    35 publications

    2.3K citations

  3. Pennsylvania State University

    State College, United States

    10 h-index

    45 publications

    2.3K citations

  4. Yale University

    New Haven, United States

    9 h-index

    35 publications

    2.3K citations

  5. Stanford University

    Stanford, United States

    6 h-index

    15 publications

    536 citations

  6. Rutgers New Jersey Medical School

    Newark, United States

    5 h-index

    21 publications

    1.4K citations

  7. University of California San Diego

    San Diego, United States

    5 h-index

    16 publications

    1.7K citations

  8. Wadsworth Center

    Albany, United States

    4 h-index

    11 publications

    334 citations

1–8 of 110

Venues

  1. Journal of Biological Chemistry

    JBC · 22 publications · 1.5K citations

    19

    h-index

  2. Biochemistry

    18 publications · 1.1K citations

    14

    h-index

  3. Nucleic Acids Research

    9 publications · 259 citations

    9

    h-index

  4. Structure

    4 publications · 255 citations

    4

    h-index

  5. Journal of the American Chemical Society

    JACS · 4 publications · 178 citations

    4

    h-index

1–5