Concepedia

Strain-promoted Cycloaddition

Strain-Promoted Cycloaddition is a type of cycloaddition reaction in which the driving force for the [3+2] or [4+2] cycloaddition between a strained alkene or alkyne and a complementary dipolar or π-system partner arises predominantly from the release of ring strain, obviating the need for a metal catalyst.

373

Publications

22.4K

Citations

1.3K

Authors

397

Institutions

Publications per year

2017–2026

121

Parents

Children

Publications

373

A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems

Nicholas J. Agard, Jennifer A. Prescher, Carolyn R. Bertozzi · Journal of the American Chemical Society · 2004 · 2.9K citations

, , +10

A New Golden Age for Donor–Acceptor Cyclopropanes

Tobias F. Schneider, Johannes Kaschel, Daniel B. Werz · Angewandte Chemie International Edition · 2014 · 1.2K citations

, , +17

Cyclobutanes in Catalysis

Tobias Seiser, Tanguy Saget, Duc N. Tran et al. · Angewandte Chemie International Edition · 2011 · 590 citations · Full text

, , +10

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

Marjoke F. Debets, Sander S. van Berkel, Sanne Schoffelen et al. · Chemical Communications · 2009 · 566 citations · Full text

, , +14

Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity

Justin M. Lopchuk, Kasper Fjelbye, Yu Kawamata et al. · Journal of the American Chemical Society · 2017 · 344 citations · Full text

, , +14

1–5 of 373

Authors

1.3K

  1. KN
    K. N. Houk

    University of California, Los Angeles, United States

    10 publications · 1.2K citations

    10

    h-index

  2. FL
    Floris L. van Delft

    Radboud University Nijmegen, Netherlands

    7 publications · 1.1K citations

    7

    h-index

  3. LR
    Luís R. Domingo

    Universitat de València, Spain

    7 publications · 232 citations

    7

    h-index

  4. BG
    Brian Gold

    Florida State University, United States

    6 publications · 379 citations

    6

    h-index

  5. GB
    Geert‐Jan Boons

    University of Georgia, United States

    6 publications · 429 citations

    6

    h-index

1–5 of 1.3K

Institutions

397

  1. Radboud University Nijmegen

    Nijmegen, The Netherlands

    13 h-index

    41 publications

    6.1K citations

  2. University of California, Los Angeles

    Los Angeles, United States

    12 h-index

    42 publications

    4.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    38 publications

    1.4K citations

  4. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    25 publications

    1.5K citations

  5. University of Georgia

    Athens, United States

    9 h-index

    35 publications

    2.4K citations

  6. University of Basel

    Basel, Switzerland

    8 h-index

    15 publications

    425 citations

  7. Universitat de València

    Valencia, Spain

    8 h-index

    12 publications

    405 citations

  8. Tokyo Institute of Technology

    Tokyo, Japan

    6 h-index

    22 publications

    910 citations

1–8 of 397

Venues

  1. Journal of the American Chemical Society

    JACS · 55 publications · 7.4K citations

    37

    h-index

  2. Angewandte Chemie International Edition

    29 publications · 3.2K citations

    22

    h-index

  3. Organic Letters

    OL · 30 publications · 1.4K citations

    21

    h-index

  4. The Journal of Organic Chemistry

    JOC · 28 publications · 804 citations

    19

    h-index

  5. Tetrahedron Letters

    25 publications · 657 citations

    17

    h-index

1–5