Concepedia

Steric Strain Engineering

Steric Strain Engineering is a methodological approach in bioorthogonal reaction design that systematically manipulates non-bonded molecular interactions to accelerate reaction kinetics by introducing controlled steric congestion that destabilizes the ground state of reagents while preserving biocompatibility.

22

Publications

901

Citations

103

Authors

37

Institutions

Publications per year

2017–2026

5

Parents

Publications

22

Chemical effects of steric strains—XIV

Herbert C. Brown, K. ICHIKAWA · Tetrahedron · 1957 · 127 citations

, , +7

Chemical effects of steric strains—XIII

Herbert C. Brown, Owen H. Wheeler, K. ICHIKAWA · Tetrahedron · 1957 · 85 citations

, , +7

A Dendritic Nanocylinder: Shape Control Through Implementation of Steric Strain

W. Stocker, Britta L. Schürmann, Jürgen P. Rabe et al. · Advanced Materials · 1998 · 77 citations

, , +10

Phenothiazine Scope: Steric Strain Induced Planarization and Excimer Formation

Deng‐Gao Chen, Yi Chen, Yi‐An Chen et al. · Angewandte Chemie International Edition · 2019 · 68 citations

, , +13

Mechanism‐Guided Engineering of ω‐Transaminase to Accelerate Reductive Amination of Ketones

Sang‐Woo Han, Eul‐Soo Park, Joo‐Young Dong et al. · Advanced Synthesis & Catalysis · 2015 · 65 citations

, , +17

1–5 of 22

Authors

103

  1. YC
    Yi Chen

    National Taiwan University, Taiwan

    2 publications · 83 citations

    2

    h-index

  2. HC
    Herbert C. Brown

    Purdue University West Lafayette, United States

    2 publications · 212 citations

    2

    h-index

  3. PC
    Pi‐Tai Chou

    National Taiwan University, Taiwan

    2 publications · 83 citations

    2

    h-index

  4. KI
    K. ICHIKAWA

    Purdue University West Lafayette, United States

    2 publications · 212 citations

    2

    h-index

  5. HT
    He Tian

    East China University of Science and Technology, China

    2 publications · 83 citations

    2

    h-index

1–5 of 103

Institutions

37

  1. East China University of Science and Technology

    Shanghai, China

    2 h-index

    8 publications

    332 citations

  2. Purdue University West Lafayette

    West Lafayette, United States

    2 h-index

    5 publications

    509 citations

  3. National Taiwan University

    Taipei, Taiwan

    2 h-index

    14 publications

    581 citations

  4. University of North Dakota

    Grand Forks, United States

    1 h-index

    4 publications

    96 citations

  5. New York University

    New York, United States

    1 h-index

    1 publications

    30 citations

  6. Center for Integrated Protein Science Munich

    Munich, Germany

    1 h-index

    2 publications

    60 citations

  7. University of Coimbra

    Coimbra, Portugal

    1 h-index

    5 publications

    140 citations

  8. Texas A&M University

    College Station, United States

    1 h-index

    5 publications

    195 citations

1–8 of 37

Venues

  1. Angewandte Chemie International Edition

    3 publications · 135 citations

    3

    h-index

  2. Organic Letters

    OL · 2 publications · 95 citations

    2

    h-index

  3. Tetrahedron

    2 publications · 212 citations

    2

    h-index

  4. Cancer Letters

    1 publications · 10 citations

    1

    h-index

  5. 1

    h-index

1–5