Concepedia

Stem Cell Differentiation Models

Stem Cell Differentiation Models is a computational or mathematical framework that specifies the dynamic processes and regulatory mechanisms by which undifferentiated stem cells transition into specialized cell types, distinguishing it from other developmental models through its focus on lineage commitment, temporal progression, and molecular control within stem cell populations.

82

Publications

4.9K

Citations

361

Authors

177

Institutions

Publications per year

2017–2026

25

Parents

Publications

82

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

Christine L. Chaffer, Ines Brueckmann, Christina Scheel et al. · Proceedings of the National Academy of Sciences · 2011 · 1.1K citations · Full text

, , +17

Elite and stochastic models for induced pluripotent stem cell generation

Shinya Yamanaka · Nature · 2009 · 518 citations

, , +13

Creating stiffness gradient polyvinyl alcohol hydrogel using a simple gradual freezing–thawing method to investigate stem cell differentiation behaviors

Tae Ho Kim, Dan Bi An, Se Heang Oh et al. · Biomaterials · 2014 · 236 citations

, , +16

Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease

Mariko Horii, Yingchun Li, Anna Wakeland et al. · Proceedings of the National Academy of Sciences · 2016 · 162 citations · Full text

, , +13

Characterization of stem cells using mathematical models of multistage cell lineages

Thomas Stiehl, Anna Marciniak‐Czochra · Mathematical and Computer Modelling · 2010 · 132 citations

, , +16

1–5 of 82

Authors

361

  1. FC
    Fabien Crauste

    Université Claude Bernard Lyon 1, France

    2 publications · 85 citations

    2

    h-index

  2. WL
    Warren L. Grayson

    Johns Hopkins University, United States

    2 publications · 26 citations

    2

    h-index

  3. AC
    Alessandro Concas

    University of Cagliari, Italy

    2 publications · 39 citations

    2

    h-index

  4. PW
    Peter W. Zandstra

    University of Toronto, Canada

    2 publications · 64 citations

    2

    h-index

  5. AA
    Alexander A. Spector

    Johns Hopkins University, United States

    2 publications · 26 citations

    2

    h-index

1–5 of 361

Institutions

177

  1. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    12 publications

    1.4K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    8 publications

    125 citations

  3. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    11 publications

    704 citations

  4. Harvard University

    Cambridge, United States

    3 h-index

    9 publications

    458 citations

  5. University of Toronto

    Toronto, Canada

    2 h-index

    7 publications

    179 citations

  6. University of Cagliari

    Cagliari, Italy

    2 h-index

    4 publications

    63 citations

  7. Rice University

    Houston, United States

    2 h-index

    8 publications

    960 citations

  8. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    2 h-index

    7 publications

    106 citations

1–8 of 177

Venues

  1. PLoS ONE

    7 publications · 171 citations

    7

    h-index

  2. PLoS Computational Biology

    4 publications · 212 citations

    4

    h-index

  3. Stem Cells

    3 publications · 163 citations

    3

    h-index

  4. BMC Systems Biology

    3 publications · 116 citations

    3

    h-index

  5. Biophysical Journal

    2 publications · 56 citations

    2

    h-index

1–5