Concepedia

Steady-state Inactivation

Steady-State Inactivation is a voltage-dependent biophysical process, belonging to the class of gating mechanisms in voltage-gated sodium channels, that characterizes the fraction of channels irreversibly transitioning into a non-conducting state following prolonged membrane depolarization, thereby distinguishing it from fast inactivation by its dependence on the duration and magnitude of the preceding voltage stimulus.

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39

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Publications

648

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Bertil Hille · The Journal of General Physiology · 1977 · 1.8K citations · Full text

, , +16

Atrial L-Type Ca <sup>2+</sup> Currents and Human Atrial Fibrillation

David R. Van Wagoner, Amber Pond, Michelle Lamorgese et al. · Circulation Research · 1999 · 587 citations · Full text

, , +17

Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neurons

ML Roy, Toshio Narahashi · Journal of Neuroscience · 1992 · 531 citations · Full text

, , +17

Simulation of the currents involved in rhythmic oscillations in thalamic relay neurons

John R. Huguenard, David A. McCormick · Journal of Neurophysiology · 1992 · 490 citations

, , +17

Cloning and Expression of a Novel Member of the Low Voltage-Activated T-Type Calcium Channel Family

Jung‐Ha Lee, Asif N. Daud, Leanne L. Cribbs et al. · Journal of Neuroscience · 1999 · 485 citations · Full text

, , +17

1–5 of 648

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  1. SG
    Stephen G. Waxman

    Yale University, United States

    12 publications · 1.6K citations

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  2. SW
    Sheng‐Nan Wu

    National Cheng Kung University, Taiwan

    11 publications · 324 citations

    11

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  3. TS
    Todd Scheuer

    University of Washington, United States

    9 publications · 1.5K citations

    9

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  4. SD
    Sulayman D. Dib‐Hajj

    Yale University, United States

    9 publications · 1.5K citations

    9

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  5. WA
    William A. Catterall

    University of Washington, United States

    8 publications · 1.3K citations

    8

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582

  1. Yale University

    New Haven, United States

    20 h-index

    73 publications

    8.6K citations

  2. Northwestern University

    Evanston, United States

    14 h-index

    34 publications

    3.2K citations

  3. Johns Hopkins University

    Baltimore, United States

    13 h-index

    47 publications

    3.1K citations

  4. University of Pennsylvania

    Philadelphia, United States

    12 h-index

    37 publications

    4.2K citations

  5. University of Calgary

    Calgary, Canada

    11 h-index

    33 publications

    2.4K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    27 publications

    1.7K citations

  7. University of Washington

    Seattle, United States

    10 h-index

    39 publications

    5.5K citations

  8. Columbia University

    New York, United States

    10 h-index

    23 publications

    1.6K citations

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  1. The Journal of Physiology

    72 publications · 5K citations

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  2. Journal of Neuroscience

    48 publications · 5.9K citations

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  3. The Journal of General Physiology

    JGP · 56 publications · 6.3K citations

    40

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  4. Journal of Neurophysiology

    JN · 44 publications · 2.6K citations

    29

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  5. Circulation Research

    29 publications · 2.9K citations

    27

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