Concepedia

Spliceosome Assembly Pathways

Spliceosome Assembly Pathways is a biological mechanism that defines the ordered sequence of macromolecular interactions and structural rearrangements through which small nuclear ribonucleoproteins and associated factors sequentially assemble on pre-mRNA to form a functional spliceosome capable of catalyzing RNA splicing.

216

Publications

17.8K

Citations

727

Authors

222

Institutions

Publications per year

2017–2026

35

Parents

Publications

216

20 Splicing of Precursors to mRNAs by the Spliceosomes

Christopher B. Burge, Thomas Tuschl, Phillip A. Sharp · 1999 · 539 citations

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Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

David Frendewey, Walter Keller · Cell · 1985 · 524 citations

, , +13

Crystal Structures of Two Sm Protein Complexes and Their Implications for the Assembly of the Spliceosomal snRNPs

Christian Kambach, Stefan Walke, Robert Young et al. · Cell · 1999 · 478 citations · Full text

, , +17

A U1 snRNA:pre‐mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site.

Bertrand Séraphin, Leo Kretzner, Michael Rosbash · The EMBO Journal · 1988 · 364 citations · Full text

, , +12

Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes

Jaime E. Arenas, John Abelson · Nature · 1991 · 357 citations

, , +11

1–5 of 216

Authors

727

  1. MR
    Michael Rosbash

    Brandeis University, United States

    13 publications · 1.6K citations

    13

    h-index

  2. RL
    Reinhard Lührmann

    Max Planck Institute for Biophysical Chemistry, Germany

    14 publications · 1.4K citations

    13

    h-index

  3. JA
    John Abelson

    California Institute of Technology, United States

    12 publications · 1.2K citations

    12

    h-index

  4. MA
    Manuel Ares

    University of California, Santa Cruz, United States

    9 publications · 643 citations

    9

    h-index

  5. AB
    Albrecht Bindereif

    Justus-Liebig-Universität Gießen, Germany

    7 publications · 457 citations

    7

    h-index

1–5 of 727

Institutions

222

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    20 h-index

    53 publications

    6.1K citations

  2. Brandeis University

    Waltham, United States

    14 h-index

    39 publications

    5.5K citations

  3. Harvard University

    Cambridge, United States

    13 h-index

    54 publications

    8.8K citations

  4. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    12 h-index

    62 publications

    5.5K citations

  5. California Institute of Technology

    Pasadena, United States

    11 h-index

    28 publications

    2.4K citations

  6. University of California, Santa Cruz

    Santa Cruz, United States

    11 h-index

    47 publications

    2.7K citations

  7. Baylor College of Medicine

    Houston, United States

    7 h-index

    16 publications

    1.5K citations

  8. University of Edinburgh

    Edinburgh, United Kingdom

    7 h-index

    20 publications

    988 citations

1–8 of 222

Venues

  1. Molecular and Cellular Biology

    MCB · 33 publications · 2.4K citations

    27

    h-index

  2. Genes & Development

    20 publications · 2.3K citations

    20

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  3. Nucleic Acids Research

    26 publications · 1.2K citations

    19

    h-index

  4. RNA

    21 publications · 895 citations

    17

    h-index

  5. Journal of Biological Chemistry

    JBC · 14 publications · 820 citations

    14

    h-index

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