Concepedia

Spindle Transfer

Spindle Transfer is a micromanipulation technique in reproductive biology wherein the metaphase II spindle–chromosome complex is extracted from an oocyte of one female and transferred into an enucleated oocyte of another female to prevent the transmission of mitochondrial DNA disorders.

17

Publications

550

Citations

110

Authors

44

Institutions

Publications per year

2017–2026

15

Variants

Maternal Spindle TransferMst

Parents

Publications

17

First pilot study of maternal spindle transfer for the treatment of repeated in vitro fertilization failures in couples with idiopathic infertility

Nuno Costa-Borges, Eros Nikitos, Katharina Späth et al. · Fertility and Sterility · 2023 · 77 citations · Full text

, , +17

Mitochondrial replacement techniques and Mexico's rule of law: on the legality of the first maternal spindle transfer case

César Palacios‐González, María de Jesús Medina Arellano · Journal of Law and the Biosciences · 2017 · 55 citations · Full text

, , +13

Sharpening the cutting edge: additional considerations for the UK debates on embryonic interventions for mitochondrial diseases

Erica Haimes, Ken Taylor · Life Sciences Society and Policy · 2017 · 49 citations · Full text

, , +17

Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

Nuno Costa-Borges, Katharina Späth, Irene Miguel-Escalada et al. · eLife · 2020 · 44 citations · Full text

, , +17

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Zhu Liu, Yike Yin et al. · Advanced Science · 2023 · 44 citations · Full text

, , +17

1–5 of 17

Authors

110

  1. KR
    Klaus Rink

    École Polytechnique Fédérale de Lausanne, Switzerland

    3 publications · 131 citations

    3

    h-index

  2. KS
    Katharina Späth

    University of Oxford, United Kingdom

    3 publications · 131 citations

    3

    h-index

  3. GC
    Gloria Calderón

    USP Institut Universitari Dexeus, Spain

    3 publications · 131 citations

    3

    h-index

  4. DW
    Dagan Wells

    University of Oxford, United Kingdom

    3 publications · 131 citations

    3

    h-index

  5. CP
    César Palacios‐González

    King's College London, United Kingdom

    3 publications · 97 citations

    3

    h-index

1–5 of 110

Institutions

44

  1. University of Oxford

    Oxford, United Kingdom

    3 h-index

    4 publications

    175 citations

  2. Center for Life Sciences

    Beijing, China

    2 h-index

    4 publications

    95 citations

  3. Science Oxford

    Oxford, United Kingdom

    2 h-index

    5 publications

    319 citations

  4. Ghent University Hospital

    Ghent, Belgium

    2 h-index

    22 publications

    649 citations

  5. Oregon Health & Science University

    Portland, United States

    2 h-index

    19 publications

    889 citations

  6. Ghent University

    Ghent, Belgium

    2 h-index

    4 publications

    115 citations

  7. Peking University

    Beijing, China

    2 h-index

    7 publications

    173 citations

  8. King's College London

    London, United Kingdom

    2 h-index

    2 publications

    80 citations

1–8 of 44

Venues

  1. Human Reproduction

    2 publications · 67 citations

    2

    h-index

  2. Fertility and Sterility

    2 publications · 87 citations

    2

    h-index

  3. Journal of Law and the Biosciences

    JLB · 2 publications · 65 citations

    2

    h-index

  4. Medicine Health Care and Philosophy

    1 publications · 25 citations

    1

    h-index

  5. Reproductive BioMedicine Online

    1 publications · 37 citations

    1

    h-index

1–5