First pilot study of maternal spindle transfer for the treatment of repeated in vitro fertilization failures in couples with idiopathic infertility

Mitochondrial gene replacement in primate offspring and embryonic stem cells

Masahito Tachibana, Michelle Sparman, Hathaitip Sritanaudomchai et al. · Nature · 2009 · 574 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Towards germline gene therapy of inherited mitochondrial diseases

Masahito Tachibana, Paula Amato, Michelle Sparman et al. · Nature · 2012 · 424 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition

Mark S. Sharpley, Christine Marciniak, Kristin Eckel‐Mahan et al. · Cell · 2012 · 407 citations · Full text

Medicine, Genetics, Molecular Genetics +14

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

Louise Hyslop, Paul Blakeley, Lyndsey Craven et al. · Nature · 2016 · 351 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations

Eunju Kang, Jun Wu, Nuria Martí Gutiérrez et al. · Nature · 2016 · 340 citations · Full text

Life Sciences, Genetics, Molecular Biology +13