Concepedia

Specific Granule Deficiency

Specific Granule Deficiency is a rare inherited phagocyte disorder characterized by impaired neutrophil secondary and tertiary granule formation, resulting in defective microbial killing and recurrent bacterial infections.

60

Publications

3.5K

Citations

303

Authors

126

Institutions

Publications per year

2017–2026

4

Variants

Sgd

Parents

Publications

60

Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.

John J. O’Shea, E J Brown, Bruce Seligmann et al. · The Journal of Immunology · 1985 · 289 citations

, , +17

Neutrophil-specific Granule Deficiency Results from a Novel Mutation with Loss of Function of the Transcription Factor CCAAT/Enhancer Binding Protein ε

Julie Lekstrom-Himes, Susan E. Dorman, Piroska Kopar et al. · The Journal of Experimental Medicine · 1999 · 200 citations · Full text

, , +16

Human neutrophil-specific granule deficiency: a model to assess the role of neutrophil-specific granules in the evolution of the inflammatory response

JI Gallin, MP Fletcher, BE Seligmann et al. · Blood · 1982 · 199 citations · Full text

, , +16

Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency.

Tomas Ganz, Julia A. Metcalf, John I. Gallin et al. · Journal of Clinical Investigation · 1988 · 195 citations · Full text

, , +14

Lactoferrin Deficiency Associated with Altered Granulocyte Function

Laurence A. Boxer, Thomas D. Coates, Richard A. Haak et al. · New England Journal of Medicine · 1982 · 172 citations

, , +14

1–5 of 60

Authors

303

  1. HP
    H. Phillip Koeffler

    Cedars-Sinai Medical Center, United States

    5 publications · 326 citations

    5

    h-index

  2. AF
    Adrian F. Gombart

    Oregon State University, United States

    5 publications · 352 citations

    5

    h-index

  3. LA
    L A Boxer

    University of Michigan, United States

    5 publications · 388 citations

    5

    h-index

  4. NB
    Niels Borregaard

    Rigshospitalet, Denmark

    5 publications · 270 citations

    5

    h-index

  5. AK
    Atsushi Komiyama

    Shinshu University, Japan

    4 publications · 290 citations

    4

    h-index

1–5 of 303

Institutions

126

  1. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    9 h-index

    37 publications

    4.2K citations

  2. University of Michigan

    Ann Arbor, United States

    7 h-index

    19 publications

    1K citations

  3. Cedars-Sinai Medical Center

    Los Angeles, United States

    6 h-index

    26 publications

    2K citations

  4. National Institutes of Health

    Bethesda, United States

    6 h-index

    20 publications

    2.1K citations

  5. Shinshu University

    Matsumoto, Japan

    5 h-index

    13 publications

    492 citations

  6. University of California, Los Angeles

    Los Angeles, United States

    5 h-index

    15 publications

    1.4K citations

  7. Yale University

    New Haven, United States

    4 h-index

    20 publications

    1.1K citations

  8. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    3 h-index

    3 publications

    106 citations

1–8 of 126

Venues

  1. Blood

    12 publications · 778 citations

    11

    h-index

  2. PubMed

    Repository · 6 publications · 282 citations

    6

    h-index

  3. The Journal of Immunology

    JI · 6 publications · 516 citations

    6

    h-index

  4. Journal of Leukocyte Biology

    JLB · 4 publications · 150 citations

    4

    h-index

  5. Journal of Clinical Investigation

    JCI · 3 publications · 343 citations

    3

    h-index

1–5