Concepedia

Spatially Variable Gene Detection

Spatially Variable Gene Detection is a computational method that identifies genes exhibiting significant spatial expression heterogeneity across tissue locations, distinguished from general differential expression analysis by explicitly modeling spatial coordinates to detect location-dependent transcriptional activity.

36

Publications

3.4K

Citations

142

Authors

71

Institutions

Publications per year

2017–2026

35

Parents

Publications

36

SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network

Jian Hu, Xiangjie Li, Kyle Coleman et al. · Nature Methods · 2021 · 1.1K citations

, , +17

SpatialDE: identification of spatially variable genes

Valentine Svensson, Sarah A. Teichmann, Oliver Stegle · Nature Methods · 2018 · 797 citations · Full text

, , +12

SPARK-X: non-parametric modeling enables scalable and robust detection of spatial expression patterns for large spatial transcriptomic studies

Jiaqiang Zhu, Shiquan Sun, Xiang Zhou · Genome biology · 2021 · 290 citations · Full text

, , +16

nnSVG for the scalable identification of spatially variable genes using nearest-neighbor Gaussian processes

Lukas M. Weber, Arkajyoti Saha, Abhirup Datta et al. · Nature Communications · 2023 · 131 citations · Full text

, , +16

SOMDE: a scalable method for identifying spatially variable genes with self-organizing map

Minsheng Hao, Kui Hua, Xuegong Zhang · Bioinformatics · 2021 · 106 citations

, , +16

1–5 of 36

Authors

142

  1. AS
    Arkajyoti Saha

    Johns Hopkins University, United States

    2 publications · 145 citations

    2

    h-index

  2. XZ
    Xiang Zhou

    University of Michigan, United States

    2 publications · 301 citations

    2

    h-index

  3. WF
    Wanwan Feng

    Shanghai Institute of Nutrition and Health, China

    2 publications · 79 citations

    2

    h-index

  4. CJ
    Callum J. Sargeant

    Walter and Eliza Hall Institute of Medical Research, Australia

    1 publications · 12 citations

    2

    h-index

  5. OS
    Oliver Stegle

    European Bioinformatics Institute, United Kingdom

    2 publications · 861 citations

    2

    h-index

1–5 of 142

Institutions

71

  1. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    9 publications

    356 citations

  2. Xi'an Jiaotong University

    Xi'an, China

    3 h-index

    3 publications

    330 citations

  3. Tsinghua University

    Beijing, China

    3 h-index

    8 publications

    414 citations

  4. The University of Melbourne

    Melbourne, Australia

    3 h-index

    17 publications

    282 citations

  5. European Molecular Biology Laboratory

    Heidelberg, Germany

    2 h-index

    2 publications

    861 citations

  6. Science for Life Laboratory

    Stockholm, Sweden

    2 h-index

    7 publications

    305 citations

  7. KTH Royal Institute of Technology

    Stockholm, Sweden

    2 h-index

    4 publications

    212 citations

  8. The University of Sydney

    Sydney, Australia

    2 h-index

    6 publications

    279 citations

1–8 of 71

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 9 publications · 198 citations

    9

    h-index

  2. Bioinformatics

    5 publications · 301 citations

    6

    h-index

  3. Nature Communications

    5 publications · 297 citations

    6

    h-index

  4. Genome biology

    3 publications · 397 citations

    4

    h-index

  5. Nature Methods

    2 publications · 1.9K citations

    2

    h-index

1–5