Concepedia

Somatic Variant Classification

Somatic Variant Classification is a computational and analytical framework within genomic medicine that distinguishes acquired genetic alterations in tumor cells from germline variants and technical artifacts by integrating sequencing evidence, biological context, and clinical significance to categorize variants according to their potential role in oncogenesis.

113

Publications

15.6K

Citations

1.2K

Authors

427

Institutions

Publications per year

2017–2026

57

Parents

Publications

113

COSMIC: somatic cancer genetics at high-resolution

Simon Forbes, David Beare, Harry Boutselakis et al. · Nucleic Acids Research · 2016 · 2.1K citations · Full text

, , +17

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

Sally Bamford, Elisabeth Dawson, Simon Forbes et al. · British Journal of Cancer · 2004 · 1.3K citations · Full text

, , +16

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

Joshua D. Campbell, Anton Alexandrov, Jaegil Kim et al. · Nature Genetics · 2016 · 1.2K citations · Full text

, , +17

Diverse somatic mutation patterns and pathway alterations in human cancers

Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson et al. · Nature · 2010 · 1K citations

, , +16

The Catalogue of Somatic Mutations in Cancer (COSMIC)

Simon Forbes, Gurpreet Bhamra, Sally Bamford et al. · Current Protocols in Human Genetics · 2008 · 918 citations · Full text

, , +16

1–5 of 113

Authors

1.2K

  1. SB
    Sally Bamford

    Wellcome Sanger Institute, United Kingdom

    5 publications · 4.3K citations

    5

    h-index

  2. SF
    Simon Forbes

    Wellcome Sanger Institute, United Kingdom

    5 publications · 4.3K citations

    5

    h-index

  3. MR
    Michael R. Stratton

    Wellcome Sanger Institute, United Kingdom

    5 publications · 3.1K citations

    5

    h-index

  4. MJ
    Matthew J. Walter

    Washington University in St. Louis, United States

    4 publications · 592 citations

    4

    h-index

  5. SE
    Sharon E. Plon

    Baylor College of Medicine, United States

    4 publications · 361 citations

    4

    h-index

1–5 of 1.2K

Institutions

427

  1. Wellcome Sanger Institute

    Cambridge, United Kingdom

    9 h-index

    117 publications

    81.3K citations

  2. Washington University in St. Louis

    St Louis, United States

    8 h-index

    41 publications

    10.2K citations

  3. Harvard University

    Cambridge, United States

    7 h-index

    25 publications

    8.9K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    45 publications

    2K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    6 h-index

    34 publications

    8.1K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    6 h-index

    26 publications

    20K citations

  7. Broad Institute

    Cambridge, United States

    6 h-index

    43 publications

    28K citations

  8. Inserm

    Paris, France

    5 h-index

    21 publications

    830 citations

1–8 of 427

Venues

  1. Genetics in Medicine

    GIM · 5 publications · 521 citations

    5

    h-index

  2. Nucleic Acids Research

    4 publications · 2.7K citations

    4

    h-index

  3. Human Mutation

    4 publications · 179 citations

    4

    h-index

  4. Blood

    4 publications · 693 citations

    4

    h-index

  5. BMC Bioinformatics

    3 publications · 92 citations

    3

    h-index

1–5