Concepedia

Solubility-permeability Interplay

Solubility-Permeability Interplay is a theoretical framework in pharmaceutical sciences that describes the dynamic relationship and mutual influence between a drug's aqueous solubility and its ability to permeate biological membranes, determining its overall absorption and bioavailability.

65

Publications

4.8K

Citations

235

Authors

87

Institutions

Publications per year

2017–2026

24

Parents

Publications

65

Cocrystals of Hydrochlorothiazide: Solubility and Diffusion/Permeability Enhancements through Drug–Coformer Interactions

Palash Sanphui, V. Kusum Devi, Deepa Clara et al. · Molecular Pharmaceutics · 2015 · 273 citations

, , +17

A Win–Win Solution in Oral Delivery of Lipophilic Drugs: Supersaturation via Amorphous Solid Dispersions Increases Apparent Solubility without Sacrifice of Intestinal Membrane Permeability

Jonathan M. Miller, Avital Beig, Robert A. Carr et al. · Molecular Pharmaceutics · 2012 · 255 citations

, , +16

A comparison between pure active pharmaceutical ingredients and therapeutic deep eutectic solvents: Solubility and permeability studies

Ana Rita C. Duarte, Ana S. D. Ferreira, Susana Barreiros et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 250 citations · Full text

, , +16

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Matteo Rossi Sebastiano, B.C. Doak, Maria Backlund et al. · Journal of Medicinal Chemistry · 2018 · 223 citations · Full text

, , +17

The Solubility–Permeability Interplay in Using Cyclodextrins as Pharmaceutical Solubilizers: Mechanistic Modeling and Application to Progesterone

Arik Dahan, Jonathan M. Miller, Amnon Hoffman et al. · Journal of Pharmaceutical Sciences · 2009 · 221 citations · Full text

, , +17

1–5 of 65

Authors

235

  1. AD
    Arik Dahan

    Ben-Gurion University of the Negev, Israel

    17 publications · 1.6K citations

    17

    h-index

  2. AB
    Avital Beig

    Ben-Gurion University of the Negev, Israel

    13 publications · 1.2K citations

    13

    h-index

  3. JM
    Jonathan M. Miller

    Ben-Gurion University of the Negev, Israel

    12 publications · 1.3K citations

    12

    h-index

  4. DL
    David Lindley

    AbbVie (United States), United States

    6 publications · 338 citations

    6

    h-index

  5. NF
    Noa Fine‐Shamir

    Ben-Gurion University of the Negev, Israel

    5 publications · 218 citations

    5

    h-index

1–5 of 235

Institutions

87

  1. Ben-Gurion University of the Negev

    Beersheba, Israel

    16 h-index

    42 publications

    3.4K citations

  2. AbbVie (United States)

    North Chicago, United States

    6 h-index

    14 publications

    834 citations

  3. University of Southern Denmark

    Odense, Denmark

    5 h-index

    12 publications

    796 citations

  4. Abbott Fund

    Chicago, United States

    4 h-index

    10 publications

    1.9K citations

  5. Manipal Academy of Higher Education

    Manipal, India

    3 h-index

    10 publications

    398 citations

  6. Monash University

    Melbourne, Australia

    3 h-index

    5 publications

    375 citations

  7. KU Leuven

    Leuven, Belgium

    3 h-index

    11 publications

    770 citations

  8. Birla Institute of Technology, Mesra

    Ranchi, India

    2 h-index

    4 publications

    114 citations

1–8 of 87

Venues

  1. Molecular Pharmaceutics

    7 publications · 994 citations

    7

    h-index

  2. Journal of Pharmaceutical Sciences

    7 publications · 684 citations

    7

    h-index

  3. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 6 publications · 611 citations

    6

    h-index

  4. European Journal of Pharmaceutical Sciences

    4 publications · 275 citations

    4

    h-index

  5. Journal of Drug Delivery Science and Technology

    JDDST · 4 publications · 116 citations

    4

    h-index

1–5