Concepedia

Solid-phase Synthesis Automation

Solid-Phase Synthesis Automation is a methodological framework within synthetic chemistry that enables the automated, stepwise assembly of organic molecules on a solid support, distinguished by its integration of resin-bound intermediates with robotic or programmable systems to streamline synthesis, purification, and high-throughput applications.

83

Publications

5.1K

Citations

312

Authors

105

Institutions

Publications per year

2017–2026

11

Parents

Publications

83

Automated Solid-Phase Synthesis of Oligosaccharides

Obadiah J. Plante, Emma R. Palmacci, Peter H. Seeberger · Science · 2001 · 936 citations

, , +15

Peptoid Polymers: A Highly Designable Bioinspired Material

Jing Sun, Ronald N. Zuckermann · ACS Nano · 2013 · 448 citations

, , +16

Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

Wojciech J. Stec, Gerald Zon, William Egan · Journal of the American Chemical Society · 1984 · 275 citations

, , +10

Solid phase synthesis of polynucleotides. VI. Farther studies on polystyrene copolymers for the solid support

Hirataka Ito, Yoshimasa Ike, Satoshi Ikuta et al. · Nucleic Acids Research · 1982 · 219 citations · Full text

, , +15

Peptide synthesis. Part 8. A system for solid-phase synthesis under low pressure continuous flow conditions

Alison Dryland, R. C. Sheppard · Journal of the Chemical Society Perkin Transactions 1 · 1986 · 191 citations

, , +10

1–5 of 83

Authors

312

  1. PH
    Peter H. Seeberger

    Max Planck Institute of Colloids and Interfaces, Germany

    10 publications · 1.4K citations

    10

    h-index

  2. GA
    Gijsbert A. van der Marel

    Leiden University, Netherlands

    4 publications · 209 citations

    4

    h-index

  3. HS
    Herman S. Overkleeft

    Leiden University, Netherlands

    3 publications · 124 citations

    3

    h-index

  4. FA
    Fernando Alberício

    Universitat de Barcelona, Spain

    3 publications · 191 citations

    3

    h-index

  5. RC
    R. C. Sheppard

    MRC Laboratory of Molecular Biology, United Kingdom

    3 publications · 298 citations

    3

    h-index

1–5 of 312

Institutions

105

  1. Max Planck Institute of Colloids and Interfaces

    Potsdam, Germany

    7 h-index

    28 publications

    1.5K citations

  2. Leiden University

    Leiden, The Netherlands

    5 h-index

    26 publications

    1.1K citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    11 publications

    3.3K citations

  4. Freie Universität Berlin

    Berlin, Germany

    3 h-index

    13 publications

    828 citations

  5. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    5 publications

    253 citations

  6. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    5 publications

    202 citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    2 h-index

    7 publications

    123 citations

  8. University of Toronto

    Toronto, Canada

    2 h-index

    8 publications

    216 citations

1–8 of 105

Venues

  1. The Journal of Organic Chemistry

    JOC · 8 publications · 414 citations

    8

    h-index

  2. Nucleic Acids Research

    6 publications · 493 citations

    6

    h-index

  3. Journal of the American Chemical Society

    JACS · 5 publications · 545 citations

    5

    h-index

  4. Organic Letters

    OL · 5 publications · 250 citations

    5

    h-index

  5. Tetrahedron Letters

    5 publications · 190 citations

    5

    h-index

1–5