Concepedia

Smad8 Activation

Smad8 Activation is a molecular signaling event within the bone morphogenetic protein pathway whereby the receptor-regulated Smad8 protein undergoes phosphorylation-mediated conformational change, enabling its translocation to the nucleus to regulate target gene transcription.

47

Publications

3.4K

Citations

312

Authors

122

Institutions

Publications per year

2017–2026

6

Parents

Publications

47

Endogenous patterns of TGFβ superfamily signaling during early <i>Xenopus</i> development

Sandrine Faure, Michelle A. Lee, Tracy Keller et al. · Development · 2000 · 251 citations

, , +17

Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells

Andrea Hoffmann · Journal of Clinical Investigation · 2006 · 247 citations · Full text

, , +17

A new nonsense mutation of <i>SMAD8</i> associated with pulmonary arterial hypertension

M Shintani, Hisato Yagi, Takahiro Nakayama et al. · Journal of Medical Genetics · 2009 · 231 citations

, , +14

Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction

Hiromasa Aoki, Makiko Fujii, Takeshi Imamura et al. · Journal of Cell Science · 2001 · 215 citations

, , +17

Smad Signaling Determines Chondrogenic Differentiation of Bone-Marrow-Derived Mesenchymal Stem Cells: Inhibition of Smad1/5/8P Prevents Terminal Differentiation and Calcification

Catharine A. Hellingman, E.N. Blaney Davidson, Wendy Koevoet et al. · Tissue Engineering Part A · 2010 · 181 citations

, , +17

1–5 of 47

Authors

312

  1. XL
    Xia Lin

    Baylor College of Medicine, United States

    3 publications · 280 citations

    3

    h-index

  2. XF
    Xin‐Hua Feng

    Zhejiang University, China

    3 publications · 280 citations

    3

    h-index

  3. HS
    Hiroshi Shibuyà

    Tokyo Medical and Dental University, Japan

    2 publications · 76 citations

    2

    h-index

  4. AH
    Andrea Hoffmann

    Medizinische Hochschule Hannover, Germany

    2 publications · 293 citations

    2

    h-index

  5. PT
    Peter ten Dijke

    Leiden University Medical Center, Netherlands

    2 publications · 408 citations

    2

    h-index

1–5 of 312

Institutions

122

  1. Harvard University

    Cambridge, United States

    4 h-index

    13 publications

    2K citations

  2. Baylor College of Medicine

    Houston, United States

    3 h-index

    13 publications

    1.1K citations

  3. Massachusetts General Hospital

    Boston, United States

    3 h-index

    5 publications

    413 citations

  4. Chungbuk National University

    Cheongju-si, South Korea

    2 h-index

    5 publications

    88 citations

  5. Kanazawa University

    Kanazawa, Japan

    2 h-index

    3 publications

    479 citations

  6. Okayama University

    Okayama, Japan

    2 h-index

    12 publications

    483 citations

  7. Emory University

    Atlanta, United States

    2 h-index

    8 publications

    548 citations

  8. Michael E. DeBakey VA Medical Center

    Houston, United States

    2 h-index

    3 publications

    183 citations

1–8 of 122

Venues

  1. Journal of Biological Chemistry

    JBC · 6 publications · 498 citations

    6

    h-index

  2. Journal of Cellular Biochemistry

    2 publications · 47 citations

    2

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 2 publications · 123 citations

    2

    h-index

  4. PLoS ONE

    2 publications · 138 citations

    2

    h-index

  5. Biochemical Journal

    BJ · 2 publications · 40 citations

    2

    h-index

1–5