Concepedia

Sirtuin-mediated Nutrient Response

Sirtuin-Mediated Nutrient Response is a molecular signaling mechanism defined by the regulation of cellular metabolism and stress resistance in response to nutrient availability through the enzymatic activity of sirtuin proteins, particularly in the context of NAD+-dependent deacetylation of target substrates.

51

Publications

10.2K

Citations

302

Authors

122

Institutions

Publications per year

2017–2026

20

Parents

Publications

51

Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1

Joseph T. Rodgers, Carles Lerín, Wilhelm Haas et al. · Nature · 2005 · 3.1K citations

, , +14

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

Jason G. Wood, Blanka Rogina, Siva Lavu et al. · Nature · 2004 · 1.9K citations

, , +16

SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

Marcia C. Haigis, Raúl Mostoslavsky, Kevin M. Haigis et al. · Cell · 2006 · 1.1K citations · Full text

, , +16

Nutrient Availability Regulates SIRT1 Through a Forkhead-Dependent Pathway

Shino Nemoto, Marı́a M. Fergusson, Toren Finkel · Science · 2004 · 671 citations

, , +16

Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

William C. Hallows, Wei Yu, Brian C. Smith et al. · Molecular Cell · 2011 · 388 citations · Full text

, , +16

1–5 of 51

Authors

302

  1. AV
    Athanassios Vassilopoulos

    National Institutes of Health, United States

    3 publications · 385 citations

    3

    h-index

  2. TA
    Tomas A. Prolla

    University of Wisconsin–Madison, United States

    3 publications · 1.6K citations

    3

    h-index

  3. LM
    Lloyd M. Smith

    University of Wisconsin–Madison, United States

    2 publications · 416 citations

    2

    h-index

  4. SH
    Shangyu Hong

    Fudan University, China

    2 publications · 288 citations

    2

    h-index

  5. KG
    Kun‐Liang Guan

    University of California San Diego, United States

    2 publications · 416 citations

    2

    h-index

1–5 of 302

Institutions

122

  1. Harvard University

    Cambridge, United States

    3 h-index

    6 publications

    13.2K citations

  2. Fudan University

    Shanghai, China

    3 h-index

    5 publications

    859 citations

  3. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    24 publications

    6.9K citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    4 publications

    10.4K citations

  5. University of California, Berkeley

    Berkeley, United States

    2 h-index

    4 publications

    248 citations

  6. Johns Hopkins University

    Baltimore, United States

    2 h-index

    5 publications

    11.6K citations

  7. Brown University

    Providence, United States

    2 h-index

    3 publications

    2.1K citations

  8. National Institute on Aging

    Baltimore, United States

    2 h-index

    3 publications

    414 citations

1–8 of 122

Venues

  1. The Journal of Nutritional Biochemistry

    JNB · 3 publications · 145 citations

    3

    h-index

  2. FEBS Letters

    2 publications · 321 citations

    2

    h-index

  3. PubMed

    Repository · 2 publications · 171 citations

    2

    h-index

  4. Genetics

    2 publications · 40 citations

    2

    h-index

  5. Molecular Cell

    2 publications · 416 citations

    2

    h-index

1–5