Concepedia

Single-nucleus Sequencing

Single-Nucleus Sequencing is a high-throughput genomic method that enables transcriptome-wide profiling of individual cells by isolating and sequencing nuclear RNA from single nuclei, thereby allowing molecular characterization of cell types and states in tissues unsuitable for whole-cell dissociation.

462

Publications

51K

Citations

5K

Authors

1.1K

Institutions

Publications per year

2017–2026

452

Variants

Sn-seqSnseq

Parents

Publications

462

Cells of the adult human heart

Monika Litviňuková, Carlos Talavera‐López, Henrike Maatz et al. · Nature · 2020 · 1.8K citations · Full text

, , +17

Comprehensive single-cell transcriptional profiling of a multicellular organism

Junyue Cao, Jonathan S. Packer, Vijay Ramani et al. · Science · 2017 · 1.6K citations · Full text

, , +15

A rapid and robust method for single cell chromatin accessibility profiling

Xi Chen, Ricardo J. Miragaia, Kedar Nath Natarajan et al. · Nature Communications · 2018 · 1.3K citations · Full text

, , +17

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

Yingyue Zhou, Wilbur M. Song, Prabhakar S. Andhey et al. · Nature Medicine · 2020 · 1.2K citations · Full text

, , +16

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

Yong Wang, Jill Waters, Marco L. Leung et al. · Nature · 2014 · 1.1K citations · Full text

, , +16

1–5 of 462

Authors

5K

  1. AR
    Aviv Regev

    Broad Institute, United States

    18 publications · 4.1K citations

    16

    h-index

  2. OR
    Orit Rozenblatt–Rosen

    Broad Institute, United States

    13 publications · 3K citations

    13

    h-index

  3. ES
    Ed S. Lein

    Allen Institute, United States

    11 publications · 2.6K citations

    11

    h-index

  4. RD
    Rebecca D. Hodge

    Allen Institute for Brain Science, United States

    11 publications · 2.6K citations

    11

    h-index

  5. BD
    Benjamin D. Humphreys

    Washington University in St. Louis, United States

    9 publications · 2.7K citations

    9

    h-index

1–5 of 5K

Institutions

1.1K

  1. Harvard University

    Cambridge, United States

    40 h-index

    326 publications

    55.7K citations

  2. Broad Institute

    Cambridge, United States

    33 h-index

    475 publications

    99.3K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    31 h-index

    90 publications

    32.1K citations

  4. University of California San Diego

    San Diego, United States

    25 h-index

    132 publications

    24.9K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    23 h-index

    93 publications

    9.7K citations

  6. Washington University in St. Louis

    St Louis, United States

    22 h-index

    202 publications

    49.1K citations

  7. Massachusetts General Hospital

    Boston, United States

    20 h-index

    111 publications

    15.1K citations

  8. Stanford University

    Stanford, United States

    19 h-index

    176 publications

    51.4K citations

1–8 of 1.1K

Venues

  1. Nature Communications

    36 publications · 5.1K citations

    30

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 73 publications · 1.9K citations

    26

    h-index

  3. Science

    18 publications · 8.2K citations

    18

    h-index

  4. Nature

    15 publications · 6.5K citations

    15

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 3K citations

    14

    h-index

1–5