Single-nucleus Rna Sequencing
Single-Nucleus RNA Sequencing is a high-throughput transcriptomic profiling method that enables the measurement of gene expression at the resolution of individual nuclei, distinguished from other single-cell RNA sequencing approaches by its reliance on isolated nuclei rather than whole cells, thereby facilitating the analysis of tissues that are difficult to dissociate or preserve intact cellular morphology.
736
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2017–2026
728
Variants
Snrna-seq
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Cells of the adult human heart
Monika Litviňuková, Carlos Talavera‐López, Henrike Maatz et al. · Nature · 2020 · 1.8K citations · Full text
Comprehensive single-cell transcriptional profiling of a multicellular organism
Junyue Cao, Jonathan S. Packer, Vijay Ramani et al. · Science · 2017 · 1.6K citations · Full text
Clonal evolution in breast cancer revealed by single nucleus genome sequencing
Yong Wang, Jill Waters, Marco L. Leung et al. · Nature · 2014 · 1.1K citations · Full text
Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain
Blue B. Lake, Rizi Ai, Gwendolyn E. Kaeser et al. · Science · 2016 · 1.1K citations · Full text
Single-cell genomics identifies cell type–specific molecular changes in autism
Lucas Schirmer, Diane Jung, Maximilian Haeussler et al. · Science · 2019 · 1K citations · Full text
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Harvard University
Cambridge, United States
44 h-index
92 publications
9.6K citations

Broad Institute
Cambridge, United States
39 h-index
81 publications
8.2K citations

Howard Hughes Medical Institute
Chevy Chase, United States
32 h-index
48 publications
9.8K citations
Massachusetts General Hospital
Boston, United States
26 h-index
37 publications
4.6K citations
Massachusetts Institute of Technology
Cambridge, United States
25 h-index
37 publications
4.6K citations

Brigham and Women's Hospital
Boston, United States
24 h-index
31 publications
5.4K citations
University of California, San Francisco
San Francisco, United States
24 h-index
28 publications
4.3K citations

Washington University in St. Louis
St Louis, United States
22 h-index
27 publications
5K citations
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