Single-Molecule Interaction Analysis is a methodological framework within single-molecule imaging that enables the direct observation and quantification of dynamic interactions between individual biomolecules in real time, distinguishing it from ensemble-averaged techniques by resolving heterogeneous behaviors and transient binding events at the molecular level.
104
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6.8K
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565
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216
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2017–2026
35
Parents
Publications
104
Probing cellular protein complexes using single-molecule pull-down
Ankur Jain, Ruijie Liu, Biswarathan Ramani et al. · Nature · 2011 · 469 citations
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565
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216
Howard Hughes Medical Institute
Chevy Chase, United States
10 h-index
21 publications
4.1K citations
Chinese Academy of Sciences
Beijing, China
6 h-index
22 publications
644 citations
University of Illinois Urbana-Champaign
Urbana, United States
6 h-index
26 publications
6.4K citations
National Institutes of Health
Bethesda, United States
5 h-index
20 publications
2.2K citations
Arizona State University
Tempe, United States
4 h-index
7 publications
530 citations
Johannes Kepler University of Linz
Linz, Austria
4 h-index
21 publications
1.3K citations
Nanjing University
Nanjing, China
3 h-index
11 publications
380 citations
Institute of Chemistry
Beijing, China
3 h-index
8 publications
342 citations
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Venues
- Angewandte Chemie International Edition
7 publications · 649 citations
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- Scientific Reports
5 publications · 120 citations
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- Biophysical Journal
5 publications · 221 citations
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- Methods
4 publications · 184 citations
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- Nature Communications
3 publications · 243 citations
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