Concepedia

Single-copy Transgene Insertion

Single-Copy Transgene Insertion is a transgenic integration event in which exactly one copy of a transgene is stably incorporated into the genome of a host organism, thereby enabling precise genetic analysis and minimizing risks of gene silencing or variable expression associated with multi-copy insertions.

98

Publications

8.7K

Citations

557

Authors

218

Institutions

Publications per year

2017–2026

25

Parents

Publications

98

Single-copy insertion of transgenes in Caenorhabditis elegans

Christian Frøkjær‐Jensen, M. Wayne Davis, Christopher E. Hopkins et al. · Nature Genetics · 2008 · 1.3K citations · Full text

, , +14

Creation of Low-Copy Integrated Transgenic Lines in <i>Caenorhabditis elegans</i>

Vida Praitis, Elizabeth Casey, David C. Collar et al. · Genetics · 2001 · 831 citations

, , +14

<i>Agrobacterium tumefaciens</i>‐mediated barley transformation

David McElroy, Roger Kalla, Sarah Fieg et al. · The Plant Journal · 1997 · 527 citations · Full text

, , +17

Single-copy transgenic mice with chosen-site integration.

Sarah K. Bronson, E. G. Plaehn, K D Kluckman et al. · Proceedings of the National Academy of Sciences · 1996 · 294 citations

, , +12

Site-specific integrase-mediated transgenesis in mice via pronuclear injection

Bosiljka Tasic, Simon Hippenmeyer, Charlene Wang et al. · Proceedings of the National Academy of Sciences · 2011 · 284 citations · Full text

, , +17

1–5 of 98

Authors

557

  1. CY
    Chia Y. Lee

    University of Arkansas for Medical Sciences, United States

    2 publications · 346 citations

    2

    h-index

  2. OS
    Oliver Smithies

    University of North Carolina at Chapel Hill, United States

    2 publications · 65 citations

    2

    h-index

  3. YS
    Yasunori Sasakura

    University of Tsukuba, Japan

    2 publications · 55 citations

    2

    h-index

  4. AH
    Akiko Hozumi

    University of Tsukuba, Japan

    2 publications · 55 citations

    2

    h-index

  5. CF
    Christian Frøkjær‐Jensen

    Howard Hughes Medical Institute, United States

    2 publications · 1.3K citations

    2

    h-index

1–5 of 557

Institutions

218

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    16 publications

    9.2K citations

  2. University of Tsukuba

    Tsukuba, Japan

    4 h-index

    10 publications

    344 citations

  3. Plant Gene Expression Center

    Albany, United States

    3 h-index

    12 publications

    2.4K citations

  4. Johns Hopkins University

    Baltimore, United States

    2 h-index

    11 publications

    786 citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    8 publications

    1.8K citations

  6. University of California, Davis

    Davis, United States

    2 h-index

    4 publications

    350 citations

  7. Duke University

    Durham, United States

    2 h-index

    16 publications

    586 citations

  8. Western Regional Research Center

    Albany, United States

    2 h-index

    10 publications

    1.4K citations

1–8 of 218

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1.1K citations

    7

    h-index

  2. PLoS ONE

    5 publications · 256 citations

    5

    h-index

  3. Nucleic Acids Research

    4 publications · 157 citations

    4

    h-index

  4. Transgenic Research

    3 publications · 171 citations

    3

    h-index

  5. Biologia Plantarum

    3 publications · 75 citations

    3

    h-index

1–5