Concepedia

Single-cell Methylation Analysis

Single-Cell Methylation Analysis is a genomic profiling technique that characterizes the distribution and dynamics of DNA methylation at the resolution of individual cells, enabling the identification of cell-type-specific epigenetic patterns and heterogeneous regulatory states within complex tissues.

73

Publications

6.4K

Citations

600

Authors

236

Institutions

Publications per year

2017–2026

59

Parents

Publications

73

Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex

Chongyuan Luo, Christopher L. Keown, Laurie Kurihara et al. · Science · 2017 · 611 citations

, , +17

DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Christof Angermueller, Heather Lee, Wolf Reik · Genome biology · 2017 · 540 citations · Full text

, , +16

Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing

Hongshan Guo, Ping Zhu, Xinglong Wu et al. · Genome Research · 2013 · 530 citations · Full text

, , +17

Simultaneous profiling of 3D genome structure and DNA methylation in single human cells

Dong-Sung Lee, Chongyuan Luo, Jingtian Zhou et al. · Nature Methods · 2019 · 359 citations

, , +17

Highly scalable generation of DNA methylation profiles in single cells

Ryan M. Mulqueen, Dmitry Pokholok, Steven Norberg et al. · Nature Biotechnology · 2018 · 330 citations · Full text

, , +15

1–5 of 73

Authors

600

  1. CL
    Chongyuan Luo

    Howard Hughes Medical Institute, United States

    6 publications · 1.4K citations

    6

    h-index

  2. JR
    Joseph R. Ecker

    Salk Institute for Biological Studies, United States

    5 publications · 1.3K citations

    5

    h-index

  3. JR
    Joseph R. Nery

    Salk Institute for Biological Studies, United States

    5 publications · 1.3K citations

    5

    h-index

  4. JZ
    Jingtian Zhou

    Salk Institute for Biological Studies, United States

    5 publications · 1.3K citations

    5

    h-index

  5. RC
    Rosa Castanon

    Salk Institute for Biological Studies, United States

    4 publications · 973 citations

    4

    h-index

1–5 of 600

Institutions

236

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    16 publications

    3.9K citations

  2. University of California, Los Angeles

    Los Angeles, United States

    6 h-index

    24 publications

    1.4K citations

  3. Babraham Institute

    Cambridge, United Kingdom

    5 h-index

    14 publications

    3K citations

  4. Peking University

    Beijing, China

    5 h-index

    34 publications

    5.2K citations

  5. Salk Institute for Biological Studies

    La Jolla, United States

    5 h-index

    83 publications

    17K citations

  6. Harvard University

    Cambridge, United States

    5 h-index

    37 publications

    2.2K citations

  7. Center for Life Sciences

    Beijing, China

    4 h-index

    5 publications

    969 citations

  8. University of California San Diego

    San Diego, United States

    4 h-index

    20 publications

    5.1K citations

1–8 of 236

Venues

  1. Nature Communications

    7 publications · 745 citations

    7

    h-index

  2. Nucleic Acids Research

    4 publications · 160 citations

    4

    h-index

  3. Nature Methods

    4 publications · 732 citations

    4

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 4 publications · 99 citations

    4

    h-index

  5. Clinical Epigenetics

    3 publications · 154 citations

    3

    h-index

1–5