Concepedia

Single-cell Haplotype Analysis

Single-Cell Haplotype Analysis is a methodological framework in genomics that resolves haplotypes at the individual cell level by integrating high-throughput sequencing with computational phasing to reconstruct allele-specific genomic architectures across somatic and germline variants.

20

Publications

1.1K

Citations

107

Authors

64

Institutions

Publications per year

2017–2026

13

Parents

Publications

20

Characterizing allele- and haplotype-specific copy numbers in single cells with CHISEL

Simone Zaccaria, Benjamin J. Raphael · Nature Biotechnology · 2020 · 187 citations · Full text

, , +14

Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes

Teng Gao, Ruslan Soldatov, Hirak Sarkar et al. · Nature Biotechnology · 2022 · 167 citations · Full text

, , +16

Dense and accurate whole-chromosome haplotyping of individual genomes

David Porubskỳ, Shilpa Garg, Ashley D. Sanders et al. · Nature Communications · 2017 · 114 citations · Full text

, , +17

Long-reads reveal that the chloroplast genome exists in two distinct versions in most plants

Weiwen Wang, Robert Lanfear · Genome Biology and Evolution · 2019 · 96 citations · Full text

, , +17

Sequencing of isolated sperm cells for direct haplotyping of a human genome

Ewen F. Kirkness, Rashel V. Grindberg, Joyclyn Yee-Greenbaum et al. · Genome Research · 2013 · 81 citations · Full text

, , +13

1–5 of 20

Authors

107

  1. DP
    David Porubskỳ

    University of Washington, United States

    5 publications · 294 citations

    5

    h-index

  2. AD
    Ashley D. Sanders

    European Molecular Biology Laboratory, Germany

    5 publications · 294 citations

    5

    h-index

  3. PM
    Peter M. Lansdorp

    University of British Columbia, Canada

    4 publications · 256 citations

    4

    h-index

  4. VG
    Victor Guryev

    University of Groningen, Netherlands

    4 publications · 256 citations

    4

    h-index

  5. TM
    Tobias Marschall

    Heinrich Heine University Düsseldorf, Germany

    3 publications · 167 citations

    3

    h-index

1–5 of 107

Institutions

64

  1. European Molecular Biology Laboratory

    Heidelberg, Germany

    4 h-index

    18 publications

    812 citations

  2. University Medical Center Groningen

    Groningen, The Netherlands

    4 h-index

    17 publications

    1.1K citations

  3. BC Cancer Agency

    Vancouver, Canada

    4 h-index

    10 publications

    646 citations

  4. University of Groningen

    Groningen, The Netherlands

    4 h-index

    17 publications

    1.1K citations

  5. University of British Columbia

    Vancouver, Canada

    4 h-index

    4 publications

    256 citations

  6. Saarland University

    Saarbrücken, Germany

    3 h-index

    5 publications

    296 citations

  7. Max Planck Institute for Informatics

    Saarbrücken, Germany

    3 h-index

    6 publications

    410 citations

  8. Peking University

    Beijing, China

    3 h-index

    17 publications

    293 citations

1–8 of 64

Venues

  1. Bioinformatics

    3 publications · 103 citations

    3

    h-index

  2. Nature Biotechnology

    3 publications · 392 citations

    3

    h-index

  3. Genome Research

    GR · 2 publications · 148 citations

    2

    h-index

  4. Molecular Human Reproduction

    MHR · 1 publications · 37 citations

    1

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 15 citations

    1

    h-index

1–5