Concepedia

Single-cell Genetic Analysis

Single-Cell Genetic Analysis is a molecular diagnostic technique that enables the comprehensive assessment of genetic and genomic profiles at the resolution of individual cells, distinguishing it from bulk analyses by revealing cellular heterogeneity and enabling precise detection of mosaicism, mutations, and chromosomal aberrations in preimplantation embryos.

201

Publications

18.1K

Citations

1.2K

Authors

417

Institutions

Publications per year

2017–2026

57

Parents

Publications

201

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

Atray Dixit, Oren Parnas, Biyu Li et al. · Cell · 2016 · 1.9K citations · Full text

, , +14

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

Takashi Nagano, Yaniv Lubling, Tim J. Stevens et al. · Nature · 2013 · 1.7K citations · Full text

, , +10

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

Zhigang Xue, Kevin Huang, Chaochao Cai et al. · Nature · 2013 · 1K citations · Full text

, , +15

Single-cell dissection of transcriptional heterogeneity in human colon tumors

Piero Dalerba, Tomer Kalisky, Debashis Sahoo et al. · Nature Biotechnology · 2011 · 730 citations

, , +16

Dissecting biological “dark matter” with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth

Yann Marcy, Cleber Ouverney, Elisabeth M. Bik et al. · Proceedings of the National Academy of Sciences · 2007 · 634 citations · Full text

, , +17

1–5 of 201

Authors

1.2K

  1. PF
    Pierre F. Ray

    Centre Hospitalier Universitaire de Grenoble, France

    8 publications · 480 citations

    8

    h-index

  2. KS
    Karen Sermon

    Vrije Universiteit Brussel, Belgium

    7 publications · 437 citations

    7

    h-index

  3. AH
    Alan H. Handyside

    Hammersmith Hospital, United Kingdom

    7 publications · 643 citations

    7

    h-index

  4. MD
    Martine De Rycke

    Universitair Ziekenhuis Brussel, Belgium

    6 publications · 350 citations

    6

    h-index

  5. IF
    I. Findlay

    University of Leeds, United Kingdom

    6 publications · 365 citations

    6

    h-index

1–5 of 1.2K

Institutions

417

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    14 publications

    9.4K citations

  2. University College London

    London, United Kingdom

    9 h-index

    19 publications

    1.4K citations

  3. Stanford University

    Stanford, United States

    8 h-index

    45 publications

    23.3K citations

  4. Harvard University

    Cambridge, United States

    6 h-index

    12 publications

    4.9K citations

  5. Hammersmith Hospital

    London, United Kingdom

    6 h-index

    12 publications

    783 citations

  6. Cornell University

    Ithaca, United States

    6 h-index

    20 publications

    973 citations

  7. University of Washington

    Seattle, United States

    6 h-index

    28 publications

    4.9K citations

  8. University of Leeds

    Leeds, United Kingdom

    6 h-index

    13 publications

    1.6K citations

1–8 of 417

Venues

  1. Molecular Human Reproduction

    MHR · 19 publications · 1.3K citations

    18

    h-index

  2. Journal of Assisted Reproduction and Genetics

    JARG · 10 publications · 411 citations

    10

    h-index

  3. Prenatal Diagnosis

    9 publications · 455 citations

    9

    h-index

  4. Scientific Reports

    8 publications · 236 citations

    8

    h-index

  5. Human Reproduction

    7 publications · 453 citations

    7

    h-index

1–5