Concepedia

Simulation-based Dosing

Simulation-Based Dosing is a computational modeling approach within pharmacometric science that uses population pharmacokinetic data and virtual patient populations to predict optimal dosing regimens, distinguished by its reliance on stochastic simulations to account for interindividual variability in geriatric patients.

43

Publications

1.3K

Citations

185

Authors

118

Institutions

Publications per year

2017–2026

16

Parents

Publications

43

Monte Carlo simulations: maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients

Jason A. Roberts, Carl M. J. Kirkpatrick, Jeffrey Lipman · Journal of Antimicrobial Chemotherapy · 2010 · 149 citations · Full text

, , +17

An Open Source Patient Simulator for Design and Evaluation of Computer Based Multiple Drug Dosing Control for Anesthetic and Hemodynamic Variables

Clara M. Ionescu, Martine Neckebroek, Mihaela Ghita et al. · IEEE Access · 2021 · 103 citations · Full text

, , +17

Hospitalized Patients With and Without Hemodialysis Have Markedly Different Vancomycin Pharmacokinetics: A Population Pharmacokinetic Model-Based Analysis

Vineet Goti, Ayyappa Chaturvedula, Michael J. Fossler et al. · Therapeutic Drug Monitoring · 2018 · 77 citations

, , +16

A Randomized Comparison of a Computer-Based Dosing Program with a Manual System to Monitor Oral Anticoagulant Therapy

Walter Ageno, Alexander G.G. Turpie · Thrombosis Research · 1998 · 61 citations

, , +12

Virtual Twins: Understanding the Data Required for Model‐Informed Precision Dosing

Thomas M. Polasek, Amin Rostami‐Hodjegan · Clinical Pharmacology & Therapeutics · 2020 · 57 citations

, , +13

1–5 of 43

Authors

185

  1. JC
    Jack Cook

    Pfizer (United States), United States

    2 publications · 92 citations

    2

    h-index

  2. DA
    David A. Stephens

    McGill University, Canada

    2 publications · 44 citations

    2

    h-index

  3. AA
    Anouk A. M. T. Donners

    Utrecht University, Netherlands

    2 publications · 35 citations

    2

    h-index

  4. RE
    Roger E. G. Schutgens

    University Medical Center Utrecht, Netherlands

    2 publications · 35 citations

    2

    h-index

  5. BR
    Benjamin Rich

    McGill University, Canada

    2 publications · 44 citations

    2

    h-index

1–5 of 185

Institutions

118

  1. University of Manchester

    Manchester, United Kingdom

    3 h-index

    3 publications

    113 citations

  2. Pfizer (United States)

    New York, United States

    2 h-index

    5 publications

    232 citations

  3. Utrecht University

    Utrecht, The Netherlands

    2 h-index

    8 publications

    150 citations

  4. Huashan Hospital

    Shanghai, China

    2 h-index

    5 publications

    98 citations

  5. McGill University Health Centre

    Montreal, Canada

    2 h-index

    3 publications

    58 citations

  6. University of Wisconsin–Madison

    Madison, United States

    2 h-index

    2 publications

    55 citations

  7. Erasmus MC

    Rotterdam, The Netherlands

    2 h-index

    5 publications

    71 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    2 publications

    62 citations

1–8 of 118

Venues

  1. International Journal of Antimicrobial Agents

    3 publications · 58 citations

    3

    h-index

  2. European Journal of Clinical Pharmacology

    2 publications · 62 citations

    2

    h-index

  3. Journal of Pharmaceutical Sciences

    2 publications · 44 citations

    2

    h-index

  4. The Journal of Clinical Pharmacology

    2 publications · 77 citations

    2

    h-index

  5. Clinical Therapeutics

    2 publications · 76 citations

    2

    h-index

1–5