Thomas M. Polasek

The ABCD of clinical pharmacokinetics

Matthew Doogue, Thomas M. Polasek · Therapeutic Advances in Drug Safety · 2013 · 132 citations · Full text

Quantitative Pharmacology, Pharmacotherapy, Gut Wall +20

Mechanism-Based Inactivation of Human Cytochrome P4502C8 by Drugs in Vitro

Thomas M. Polasek, David J. Elliot, Benjamin C. Lewis et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 95 citations

Perpetrators of pharmacokinetic drug–drug interactions arising from altered cytochrome P450 activity: a criteria‐based assessment

Thomas M. Polasek, Frank Lin, John O. Miners et al. · British Journal of Clinical Pharmacology · 2011 · 88 citations · Full text

Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate

Thomas M. Polasek, John O. Miners · European Journal of Clinical Pharmacology · 2006 · 82 citations

Drug Target, Pharmacological Study, Biochemistry +9

An evaluation of potential mechanism‐based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid

Thomas M. Polasek, David J. Elliot, Andrew A. Somogyi et al. · British Journal of Clinical Pharmacology · 2006 · 76 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Pharmacodynamic Modeling +20