Concepedia

Side-chain Repacking

Side-Chain Repacking is a computational method in structural biology that refines the three-dimensional conformation of amino acid side chains within a protein scaffold by optimizing their rotameric states to minimize steric clashes and energy while maintaining the backbone structure.

13

Publications

2.8K

Citations

52

Authors

29

Institutions

Publications per year

2017–2026

3

Parents

Publications

13

GalaxyRefine: protein structure refinement driven by side-chain repacking

Lim Heo, Hahnbeom Park, Chaok Seok · Nucleic Acids Research · 2013 · 1.4K citations · Full text

, , +15

Modeling structurally variable regions in homologous proteins with rosetta

Carol A. Rohl, Charlie E. M. Strauss, Dylan Chivian et al. · Proteins Structure Function and Bioinformatics · 2004 · 328 citations

, , +17

Flex ddG: Rosetta Ensemble-Based Estimation of Changes in Protein–Protein Binding Affinity upon Mutation

Kyle A. Barlow, Shane Ó Conchúir, Samuel Thompson et al. · The Journal of Physical Chemistry B · 2018 · 320 citations

, , +17

The Backrub Motion: How Protein Backbone Shrugs When a Sidechain Dances

Ian Davis, W.B. Arendall, David Richardson et al. · Structure · 2006 · 269 citations · Full text

, , +16

Derivation and testing of pair potentials for protein folding. When is the quasichemical approximation correct?

Jeffrey Skolnick, Adam Godzik, Lukasz Jaroszewski et al. · Protein Science · 1997 · 206 citations · Full text

, , +17

1–5 of 13

Authors

52

  1. AE
    Amy E. Keating

    Massachusetts Institute of Technology, United States

    2 publications · 139 citations

    2

    h-index

  2. LL
    Li Li

    Massachusetts General Hospital, United States

    1 publications · 39 citations

    1

    h-index

  3. VW
    Violetta Weinreb

    University of North Carolina at Chapel Hill, United States

    1 publications · 39 citations

    1

    h-index

  4. CA
    Carol A. Rohl

    University of Washington, United States

    1 publications · 328 citations

    1

    h-index

  5. AV
    Alejandro Virrueta

    Yale University, United States

    1 publications · 10 citations

    1

    h-index

1–5 of 52

Institutions

29

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    6 publications

    1K citations

  2. Codexis (United States)

    Redwood City, United States

    1 h-index

    1 publications

    16 citations

  3. Aalto University

    Espoo, Finland

    1 h-index

    1 publications

    320 citations

  4. Yale University

    New Haven, United States

    1 h-index

    4 publications

    40 citations

  5. Hebrew University of Jerusalem

    Jerusalem, Israel

    1 h-index

    3 publications

    66 citations

  6. Institut Pasteur

    Paris, France

    1 h-index

    1 publications

    39 citations

  7. University of California, San Francisco

    San Francisco, United States

    1 h-index

    6 publications

    1.9K citations

  8. Duke University

    Durham, United States

    1 h-index

    4 publications

    1.1K citations

1–8 of 29

Venues

  1. Proteins Structure Function and Bioinformatics

    5 publications · 444 citations

    5

    h-index

  2. Nucleic Acids Research

    1 publications · 1.4K citations

    1

    h-index

  3. Protein Science

    PS · 1 publications · 206 citations

    1

    h-index

  4. The Journal of Physical Chemistry B

    1 publications · 320 citations

    1

    h-index

  5. Structure

    1 publications · 269 citations

    1

    h-index

1–5