Concepedia

Sic1 Accumulation

Sic1 Accumulation is a regulatory mechanism in the cell cycle characterized by the progressive build-up of the cyclin-dependent kinase inhibitor Sic1, which enforces the irreversible transition from mitosis to G1 phase by preventing premature cyclin-dependent kinase reactivation.

14

Publications

840

Citations

71

Authors

25

Institutions

Publications per year

2017–2026

0

Parents

Publications

14

Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase

Mardo Kõivomägi, Ervin Valk, Rainis Venta et al. · Nature · 2011 · 212 citations

, , +8

The Transcription Factor Swi5 Regulates Expression of the Cyclin Kinase Inhibitor p40<sup><i>SIC1</i></sup>

Dunja Knapp, Leena T. Bhoite, David J. Stillman et al. · Molecular and Cellular Biology · 1996 · 129 citations · Full text

, , +17

Analysis of Polyubiquitin Conjugates Reveals That the Rpn10 Substrate Receptor Contributes to the Turnover of Multiple Proteasome Targets

Thibault Mayor, J. Russell Lipford, Johannes Graumann et al. · Molecular & Cellular Proteomics · 2005 · 101 citations · Full text

, , +13

DH334, a β-carboline anti-cancer drug, Inhibits the CDK activity of budding yeast

Yan Li, Fengshan Liang, Wei Jiang et al. · Cancer Biology & Therapy · 2007 · 77 citations

, , +15

Rapamycin‐mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in <i>Saccharomyces cerevisiae</i>

Vittoria Zinzalla, Michele Graziola, Andrea Mastriani et al. · Molecular Microbiology · 2007 · 67 citations · Full text

, , +17

1–5 of 14

Authors

71

  1. MV
    Marco Vanoni

    University of Milano-Bicocca, Italy

    2 publications · 95 citations

    2

    h-index

  2. LA
    Lilia Alberghina

    University of Milano-Bicocca, Italy

    2 publications · 95 citations

    2

    h-index

  3. AM
    Andrea Mastriani

    University of Milano-Bicocca, Italy

    2 publications · 95 citations

    2

    h-index

  4. VZ
    Vittoria Zinzalla

    University of Milano-Bicocca, Italy

    2 publications · 95 citations

    2

    h-index

  5. ML
    Martin Lepiku

    University of Tartu, Estonia

    1 publications · 212 citations

    1

    h-index

1–5 of 71

Institutions

25

  1. University of Milano-Bicocca

    Milan, Italy

    2 h-index

    5 publications

    296 citations

  2. University of California, San Francisco

    San Francisco, United States

    2 h-index

    3 publications

    286 citations

  3. National Institute of Advanced Industrial Science and Technology

    Tsukuba, Japan

    1 h-index

    3 publications

    30 citations

  4. Schlumberger (Ireland)

    Dublin, Ireland

    1 h-index

    1 publications

    22 citations

  5. Thomas Jefferson University

    Philadelphia, United States

    1 h-index

    4 publications

    148 citations

  6. Max Delbrück Center

    Berlin, Germany

    1 h-index

    1 publications

    10 citations

  7. Boehringer Ingelheim (Germany)

    Ingelheim, Germany

    1 h-index

    3 publications

    147 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    5 publications

    505 citations

1–8 of 25

Venues

  1. Cell Cycle

    2 publications · 50 citations

    2

    h-index

  2. Molecular and Cellular Biology

    MCB · 2 publications · 166 citations

    2

    h-index

  3. Genetics

    1 publications · 46 citations

    1

    h-index

  4. Nature

    1 publications · 212 citations

    1

    h-index

  5. PLoS ONE

    1 publications · 12 citations

    1

    h-index

1–5