Concepedia

Shared Neoantigens

Shared Neoantigens is a class of tumor-specific antigens arising from recurrent somatic mutations that are identically present across multiple patients or tumor types, distinguished from private neoantigens by their occurrence in disparate individuals and potential for broad applicability in off-the-shelf neoantigen-targeted immunotherapies.

21

Publications

1.3K

Citations

267

Authors

88

Institutions

Publications per year

2017–2026

19

Parents

Publications

21

Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers

Parisa Malekzadeh, Anna Pasetto, Paul F. Robbins et al. · Journal of Clinical Investigation · 2019 · 269 citations · Full text

, , +17

The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution

Alexej Ballhausen, Moritz J. Przybilla, Michael Jendrusch et al. · Nature Communications · 2020 · 131 citations · Full text

, , +17

A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results

Amy Rappaport, Chrisann Kyi, Monica Lane et al. · Nature Medicine · 2024 · 127 citations

, , +17

TSNAdb: A Database for Tumor-Specific Neoantigens from Immunogenomics Data Analysis

Jingcheng Wu, Wenyi Zhao, Binbin Zhou et al. · Genomics Proteomics & Bioinformatics · 2018 · 115 citations · Full text

, , +17

Pan-cancer proteogenomics expands the landscape of therapeutic targets

Sara R. Savage, Xinpei Yi, Jonathan T. Lei et al. · Cell · 2024 · 105 citations · Full text

, , +17

1–5 of 21

Authors

267

  1. CS
    Chunxia Su

    Shanghai Pulmonary Hospital, China

    1 publications · 30 citations

    1

    h-index

  2. SG
    Sophie Gardrat

    Institut Curie, France

    1 publications · 89 citations

    1

    h-index

  3. OG
    Olivier Ganier

    Centre National de la Recherche Scientifique, France

    1 publications · 89 citations

    1

    h-index

  4. DP
    Deepak Perumal

    Icahn School of Medicine at Mount Sinai, United States

    1 publications · 86 citations

    1

    h-index

  5. YD
    Yongchao Dou

    Baylor College of Medicine, United States

    1 publications · 105 citations

    1

    h-index

1–5 of 267

Institutions

88

  1. University of Copenhagen

    Copenhagen, Denmark

    2 h-index

    5 publications

    70 citations

  2. Fudan University

    Shanghai, China

    2 h-index

    4 publications

    430 citations

  3. Copenhagen University Hospital

    Copenhagen, Denmark

    2 h-index

    11 publications

    155 citations

  4. Tongji University

    Shanghai, China

    1 h-index

    4 publications

    120 citations

  5. University of Vienna

    Vienna, Austria

    1 h-index

    2 publications

    62 citations

  6. Baylor College of Medicine

    Houston, United States

    1 h-index

    13 publications

    1.4K citations

  7. University of South China

    Hengyang, China

    1 h-index

    1 publications

    78 citations

  8. Iowa State University

    Ames, United States

    1 h-index

    1 publications

    115 citations

1–8 of 88

Venues

  1. Nature Communications

    2 publications · 209 citations

    2

    h-index

  2. Genomics Proteomics & Bioinformatics

    1 publications · 115 citations

    1

    h-index

  3. Acta Neuropathologica

    1 publications · 31 citations

    1

    h-index

  4. Cell

    1 publications · 105 citations

    1

    h-index

  5. PLoS ONE

    1 publications · 51 citations

    1

    h-index

1–5