Concepedia

Serotonergic Toxicity

Serotonergic Toxicity is a clinical syndrome characterized by excessive serotonergic neurotransmission in the central nervous system, resulting from the overactivation of serotonin receptors, particularly the 5-HT2A subtype, due to the administration or interaction of serotonergic agents.

169

Publications

8.5K

Citations

601

Authors

246

Institutions

Publications per year

2017–2026

20

Variants

Serotonin Syndrome

Parents

Publications

169

The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity

E.J.C. Dunkley, Geoffrey K. Isbister, David Sibbritt et al. · QJM · 2003 · 1K citations · Full text

, , +15

Serotonin Neurotoxicity after (±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”): A Controlled Study in Humans

Una D. McCann, Alison Ridenour, Yavin Shaham et al. · Neuropsychopharmacology · 1994 · 335 citations

, , +16

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

G.A. Ricaurte, L.E. DeLanney, Ian Irwin et al. · Brain Research · 1988 · 249 citations

, , +16

Developmental Exposure of Rats to Chlorpyrifos Leads to Behavioral Alterations in Adulthood, Involving Serotonergic Mechanisms and Resembling Animal Models of Depression

Justin E Aldridge, Edward D. Levin, Frederic J. Seidler et al. · Environmental Health Perspectives · 2005 · 233 citations · Full text

, , +17

Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson's disease

I Richard, Roger Kurlan, Caroline M. Tanner et al. · Neurology · 1997 · 232 citations

, , +17

1–5 of 169

Authors

601

  1. FJ
    Frederic J. Seidler

    Duke Medical Center, United States

    5 publications · 513 citations

    5

    h-index

  2. TA
    Theodore A. Slotkin

    Duke Medical Center, United States

    5 publications · 513 citations

    5

    h-index

  3. GK
    Geoffrey K. Isbister

    University of Newcastle Australia, Australia

    4 publications · 1.1K citations

    4

    h-index

  4. RB
    Richard B. Rothman

    National Institute on Drug Abuse, United States

    4 publications · 193 citations

    4

    h-index

  5. IM
    Ian M. Whyte

    University of Newcastle Australia, Australia

    3 publications · 1.1K citations

    3

    h-index

1–5 of 601

Institutions

246

  1. Johns Hopkins University

    Baltimore, United States

    8 h-index

    15 publications

    1.5K citations

  2. Duke Medical Center

    Durham, United States

    5 h-index

    12 publications

    1.1K citations

  3. University of Newcastle Australia

    Newcastle, Australia

    5 h-index

    12 publications

    1.5K citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    5 h-index

    9 publications

    640 citations

  5. National Institute on Drug Abuse

    Bethesda, United States

    5 h-index

    18 publications

    867 citations

  6. Oregon Health & Science University

    Portland, United States

    4 h-index

    7 publications

    228 citations

  7. Duke University Hospital

    Durham, United States

    4 h-index

    10 publications

    833 citations

  8. University of Colorado Denver

    Denver, United States

    3 h-index

    7 publications

    95 citations

1–8 of 246

Venues

  1. PubMed

    Repository · 17 publications · 725 citations

    15

    h-index

  2. Brain Research

    10 publications · 766 citations

    10

    h-index

  3. Journal of Medical Toxicology

    6 publications · 249 citations

    6

    h-index

  4. Clinical Toxicology

    6 publications · 296 citations

    6

    h-index

  5. 4

    h-index

1–5