Concepedia

Sequential Trial Emulation

Sequential Trial Emulation is a type of target trial emulation that sequentially reconfigures observational data over time to emulate multiple consecutive randomized trials, thereby enabling dynamic assessment of time-varying treatment effects under a prespecified causal framework.

7

Publications

273

Citations

67

Authors

42

Institutions

Publications per year

2017–2026

6

Variants

Sequential Target Trial Emulation

Parents

Publications

7

Overrunning and underrunning in sequential clinical trials

John Whitehead · Controlled Clinical Trials · 1992 · 94 citations

, , +9

Emulating a Novel Clinical Trial Using Existing Observational Data. Predicting Results of the PreVent Study

Andrew J. Admon, John P. Donnelly, Jonathan D. Casey et al. · Annals of the American Thoracic Society · 2019 · 75 citations · Full text

, , +16

Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data

William Hulme, Elizabeth Williamson, Elsie Horne et al. · Annals of Internal Medicine · 2023 · 32 citations · Full text

, , +17

Glucarpidase for treatment of high-dose methotrexate toxicity

Shruti Gupta, Sarah Allison Kaunfer, Kevin L. Chen et al. · Blood · 2025 · 30 citations · Full text

, , +17

Head-to-head comparison of FOLFIRINOX versus gemcitabine plus nab-paclitaxel in advanced pancreatic cancer: a target trial emulation using real-world data

Devon J. Boyne, Darren R. Brenner, Alind Gupta et al. · Annals of Epidemiology · 2022 · 21 citations

, , +11

1–5 of 7

Authors

67

  1. MA
    Miguel A. Hernán

    Harvard University, United States

    2 publications · 53 citations

    2

    h-index

  2. AJ
    Andrew J. Admon

    University of Michigan, United States

    1 publications · 75 citations

    1

    h-index

  3. BL
    Beini Lyu

    University of Wisconsin–Madison, United States

    1 publications · 19 citations

    1

    h-index

  4. EC
    Edward Chia‐Cheng Lai

    National Cheng Kung University, Taiwan

    1 publications · 18 citations

    1

    h-index

  5. LA
    Laurie A. Tomlinson

    London School of Hygiene & Tropical Medicine, United Kingdom

    1 publications · 32 citations

    1

    h-index

1–5 of 67

Institutions

42

  1. University of Michigan

    Ann Arbor, United States

    2 h-index

    2 publications

    94 citations

  2. Universitat de Barcelona

    Barcelona, Spain

    1 h-index

    1 publications

    18 citations

  3. Lahey Hospital and Medical Center

    Burlington, United States

    1 h-index

    2 publications

    150 citations

  4. Harvard University

    Cambridge, United States

    1 h-index

    1 publications

    32 citations

  5. National Defense Medical Center

    Taipei, Taiwan

    1 h-index

    1 publications

    18 citations

  6. Vanderbilt University Medical Center

    Nashville, United States

    1 h-index

    3 publications

    225 citations

  7. VA Center for Clinical Management Research

    Ann Arbor, United States

    1 h-index

    2 publications

    150 citations

  8. Health Services Research & Development

    Washington, United States

    1 h-index

    2 publications

    150 citations

1–8 of 42

Venues

  1. American Journal of Kidney Diseases

    AJKD · 1 publications · 19 citations

    1

    h-index

  2. Controlled Clinical Trials

    1 publications · 94 citations

    1

    h-index

  3. Annals of Epidemiology

    1 publications · 21 citations

    1

    h-index

  4. Annals of the American Thoracic Society

    1 publications · 75 citations

    1

    h-index

  5. Epidemiology

    1 publications · 14 citations

    1

    h-index

1–5