Concepedia

Sepsis De-escalation

Sepsis De-Escalation is a clinical decision-making framework within antimicrobial stewardship that involves the systematic refinement of broad-spectrum antibiotic therapy in sepsis patients, based on microbial etiology and host response, to optimize treatment precision while minimizing resistance and toxicity.

47

Publications

14.7K

Citations

411

Authors

239

Institutions

Publications per year

2017–2026

16

Parents

Publications

47

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.8K citations · Full text

, , +15

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

&NA; · Survey of Anesthesiology · 2002 · 664 citations

, , +15

EARLY GOAL-DIRECTED THERAPY IN THE TREATMENT OF SEVERE SEPSIS AND SEPTIC SHOCK

&NA; · Infectious Diseases in Clinical Practice · 2002 · 517 citations

, , +15

De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock

José Garnacho‐Montero, Ana Escoresca‐Ortega, Y. Corcia-Palomo et al. · Intensive Care Medicine · 2013 · 389 citations · Full text

, , +14

Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study

Edward Abraham, Konrad Reinhart, Petr Svoboda et al. · Critical Care Medicine · 2001 · 253 citations

, , +16

1–5 of 47

Authors

411

  1. JV
    Jean‐Louis Vincent

    Erasmus Hospital, Belgium

    3 publications · 175 citations

    3

    h-index

  2. ML
    Marc Léone

    Hôpital Nord, France

    3 publications · 566 citations

    3

    h-index

  3. JR
    Jordi Rello

    Universitat Autònoma de Barcelona, Spain

    3 publications · 361 citations

    3

    h-index

  4. MH
    Marin H. Kollef

    Washington University in St. Louis, United States

    2 publications · 46 citations

    2

    h-index

  5. AA
    Apostolos Armaganidis

    National and Kapodistrian University of Athens, Greece

    2 publications · 102 citations

    2

    h-index

1–5 of 411

Institutions

239

  1. Washington University in St. Louis

    St Louis, United States

    3 h-index

    3 publications

    230 citations

  2. National and Kapodistrian University of Athens

    Athens, Greece

    3 h-index

    14 publications

    854 citations

  3. Assistance Publique Hôpitaux de Marseille

    Marseille, France

    3 h-index

    4 publications

    700 citations

  4. Hôpital Nord

    Marseille, France

    3 h-index

    9 publications

    1.9K citations

  5. Aix-Marseille Université

    Marseille, France

    3 h-index

    7 publications

    1.4K citations

  6. Université Paris Cité

    Paris, France

    2 h-index

    2 publications

    318 citations

  7. Université de Nîmes

    Nîmes, France

    2 h-index

    2 publications

    432 citations

  8. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    3 publications

    476 citations

1–8 of 239

Venues

  1. Intensive Care Medicine

    5 publications · 965 citations

    5

    h-index

  2. BMC Infectious Diseases

    3 publications · 173 citations

    3

    h-index

  3. Infection

    2 publications · 81 citations

    2

    h-index

  4. Clinical Microbiology and Infection

    CMI · 2 publications · 197 citations

    2

    h-index

  5. Critical Care Medicine

    2 publications · 355 citations

    2

    h-index

1–5