Concepedia

Separase-mediated Cleavage

Separase-Mediated Cleavage is a biochemical mechanism, belonging to the class of post-translational modifications, wherein the protease separase selectively cleaves the cohesin subunit Rad21 to trigger sister chromatid separation during anaphase.

120

Publications

9.7K

Citations

509

Authors

171

Institutions

Publications per year

2017–2026

21

Parents

Publications

120

Cohesin Cleavage by Separase Required for Anaphase and Cytokinesis in Human Cells

Silke Hauf, Irene C. Waizenegger, Jan‐Michael Peters · Science · 2001 · 506 citations

, , +17

Dissociation of Cohesin from Chromosome Arms and Loss of Arm Cohesion during Early Mitosis Depends on Phosphorylation of SA2

Silke Hauf, Elisabeth Roitinger, Birgit Koch et al. · PLoS Biology · 2005 · 442 citations · Full text

, , +17

Separase, Polo Kinase, the Kinetochore Protein Slk19, and Spo12 Function in a Network that Controls Cdc14 Localization during Early Anaphase

Frank Stegmeier, Rosella Visintin, Angelika Amon · Cell · 2002 · 439 citations · Full text

, , +16

Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin

Sara B.C. Buonomo, Rosemary K. Clyne, Jörg Fuchs et al. · Cell · 2000 · 431 citations · Full text

, , +16

Shugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells

Barry E. McGuinness, Toru Hirota, N. Kudo et al. · PLoS Biology · 2005 · 364 citations · Full text

, , +17

1–5 of 120

Authors

509

  1. OS
    Olaf Stemmann

    Max Planck Institute of Biochemistry, Germany

    14 publications · 897 citations

    14

    h-index

  2. DP
    Debananda Pati

    Children's Cancer Center, United States

    7 publications · 394 citations

    7

    h-index

  3. MY
    Mitsuhiro Yanagida

    Kyoto University, Japan

    7 publications · 330 citations

    7

    h-index

  4. KN
    Kim Nasmyth

    Research Institute of Molecular Pathology, Austria

    7 publications · 1.7K citations

    7

    h-index

  5. FU
    Frank Uhlmann

    The Francis Crick Institute, United Kingdom

    6 publications · 1.2K citations

    6

    h-index

1–5 of 509

Institutions

171

  1. Research Institute of Molecular Pathology

    Vienna, Austria

    13 h-index

    56 publications

    14.2K citations

  2. Max Planck Institute of Biochemistry

    Martinsried, Germany

    11 h-index

    34 publications

    2K citations

  3. University of Bayreuth

    Bayreuth, Germany

    11 h-index

    32 publications

    1.7K citations

  4. Baylor College of Medicine

    Houston, United States

    10 h-index

    58 publications

    3.9K citations

  5. The University of Tokyo

    Tokyo, Japan

    7 h-index

    27 publications

    1.8K citations

  6. Children's Cancer Center

    Tampa, United States

    7 h-index

    41 publications

    2.8K citations

  7. Max Planck Society

    Munich, Germany

    6 h-index

    11 publications

    1K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    42 publications

    2.6K citations

1–8 of 171

Venues

  1. Cell Cycle

    11 publications · 393 citations

    11

    h-index

  2. PLoS ONE

    7 publications · 159 citations

    7

    h-index

  3. Journal of Biological Chemistry

    JBC · 7 publications · 286 citations

    7

    h-index

  4. Nature

    7 publications · 531 citations

    7

    h-index

  5. Developmental Cell

    5 publications · 767 citations

    5

    h-index

1–5