Concepedia

Selectivity Metrics

Selectivity Metrics is a methodological framework in computational chemistry and bioinformatics that quantifies the relative specificity of a molecule or agent in interacting with a target system over off-target systems, distinguishing it from general affinity measures by emphasizing discriminatory performance across multiple binding or functional outcomes.

307

Publications

18.9K

Citations

949

Authors

130

Institutions

Publications per year

2017–2026

13

Parents

Publications

307

Tris(phenanthroline)ruthenium(II): stereoselectivity in binding to DNA

Jacqueline K. Barton, Avis T. Danishefsky, Jonathan M. Goldberg · Journal of the American Chemical Society · 1984 · 979 citations

, , +9

Philicity:  A Unified Treatment of Chemical Reactivity and Selectivity

Pratim Kumar Chattaraj, Buddhadev Maiti, Utpal Sarkar · The Journal of Physical Chemistry A · 2003 · 816 citations

, , +14

New rules of selectivity: allylic alkylations catalyzed by palladium

Barry M. Trost · Accounts of Chemical Research · 1980 · 632 citations

, , +13

The Dendritic Box: Shape-Selective Liberation of Encapsulated Guests

Johan F. G. A. Jansen, E. W. Meijer, Ellen M. M. de Brabander‐van den Berg · Journal of the American Chemical Society · 1995 · 457 citations · Full text

, , +9

Crown Ethers:  The Search for Selective Ion Ligating Agents

Jerald S. Bradshaw, Reed M. Izatt · Accounts of Chemical Research · 1997 · 387 citations

, , +10

1–5 of 307

Authors

949

  1. KN
    K. N. Houk

    University of California, Los Angeles, United States

    5 publications · 598 citations

    5

    h-index

  2. CN
    Carl Niemann

    California Institute of Technology, United States

    4 publications · 217 citations

    4

    h-index

  3. JB
    Jürgen Bajorath

    University of Bonn, Germany

    4 publications · 109 citations

    4

    h-index

  4. GE
    George E. Hein

    California Institute of Technology, United States

    4 publications · 217 citations

    4

    h-index

  5. JJ
    J. J. Dannenberg

    City University of New York, United States

    4 publications · 158 citations

    4

    h-index

1–5 of 949

Institutions

130

  1. University of Minnesota

    Minneapolis, United States

    4 h-index

    4 publications

    206 citations

  2. University of Bonn

    Bonn, Germany

    4 h-index

    12 publications

    349 citations

  3. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    3 h-index

    4 publications

    185 citations

  4. Scripps Research Institute

    San Diego, United States

    2 h-index

    11 publications

    403 citations

  5. University of California, Berkeley

    Berkeley, United States

    2 h-index

    9 publications

    519 citations

  6. Indiana University Bloomington

    Bloomington, United States

    2 h-index

    6 publications

    770 citations

  7. Yale University

    New Haven, United States

    2 h-index

    6 publications

    102 citations

  8. Development Bank of Japan

    Tokyo, Japan

    2 h-index

    5 publications

    364 citations

1–8 of 130

Venues

  1. Journal of the American Chemical Society

    JACS · 113 publications · 8.4K citations

    48

    h-index

  2. The Journal of Organic Chemistry

    JOC · 89 publications · 3.9K citations

    35

    h-index

  3. The Journal of Physical Chemistry

    16 publications · 837 citations

    14

    h-index

  4. Journal of Medicinal Chemistry

    12 publications · 571 citations

    12

    h-index

  5. Biochemistry

    12 publications · 483 citations

    11

    h-index

1–5