Concepedia

Selectivity Index Optimization

Selectivity Index Optimization is a computational or experimental methodology designed to maximize the ratio of on-target to off-target effects in therapeutic interventions, thereby enhancing the specificity and safety of bioactive agents.

77

Publications

2.8K

Citations

509

Authors

191

Institutions

Publications per year

2017–2026

33

Parents

Publications

77

Antiviral Activity of Glycyrrhizic Acid Derivatives against SARS−Coronavirus

Gerold Hoever, Martin Michaelis, Lia A. Baltina et al. · Journal of Medicinal Chemistry · 2005 · 418 citations

, , +13

Modified flotation rate constant and selectivity index

Manqiu Xu · Minerals Engineering · 1998 · 130 citations

, , +8

Synthesis, Cytotoxicity, and Anti-<i>Trypanosoma cruzi</i> Activity of New Chalcones

José C. Aponte, Manuela Verástegui, Edith Málaga et al. · Journal of Medicinal Chemistry · 2008 · 120 citations

, , +15

Effect of glycounits on the antimicrobial properties and toxicity behavior of polymers based on quaternized DMAEMA

Marta Álvarez‐Paino, Alexandra Muñoz‐Bonilla, Fátima López et al. · Biomacromolecules · 2014 · 90 citations · Full text

, , +14

Design and Synthesis of Dipeptidyl Glutaminyl Fluoromethyl Ketones as Potent Severe Acute Respiratory Syndrome Coronovirus (SARS-CoV) Inhibitors

Han‐Zhong Zhang, Hong Zhang, William Kemnitzer et al. · Journal of Medicinal Chemistry · 2006 · 85 citations

, , +15

1–5 of 77

Authors

509

  1. KY
    Kazumi Yokomizo

    Kumamoto University, Japan

    2 publications · 53 citations

    2

    h-index

  2. CB
    Colleen B. Jonsson

    Southern Research Institute, United States

    2 publications · 48 citations

    2

    h-index

  3. KS
    Kunihiro Sumoto

    Fukuoka University, Japan

    2 publications · 53 citations

    2

    h-index

  4. HW
    Hans Wilhelm Doerr

    Goethe University Frankfurt, Germany

    2 publications · 503 citations

    2

    h-index

  5. HB
    Haridas B. Rode

    Indian Institute of Chemical Technology, India

    2 publications · 52 citations

    2

    h-index

1–5 of 509

Institutions

191

  1. Ufa Institute of Chemistry

    Ufa, Russia

    3 h-index

    8 publications

    2.1K citations

  2. Academy of Scientific and Innovative Research

    Ghaziabad, India

    3 h-index

    13 publications

    268 citations

  3. Tabriz University of Medical Sciences

    Tabriz, Iran

    3 h-index

    4 publications

    85 citations

  4. Shahid Beheshti University of Medical Sciences

    Tehran, Iran

    3 h-index

    7 publications

    170 citations

  5. Fukuoka University

    Fukuoka, Japan

    2 h-index

    14 publications

    371 citations

  6. King Saud University

    Riyadh, Saudi Arabia

    2 h-index

    6 publications

    192 citations

  7. Badr University in Cairo

    Cairo, Egypt

    2 h-index

    2 publications

    32 citations

  8. Sojo University

    Kumamoto, Japan

    2 h-index

    10 publications

    265 citations

1–8 of 191

Venues

  1. Journal of Medicinal Chemistry

    15 publications · 1.1K citations

    15

    h-index

  2. Molecules

    7 publications · 167 citations

    7

    h-index

  3. 5

    h-index

  4. ACS Medicinal Chemistry Letters

    3 publications · 61 citations

    3

    h-index

  5. Archiv der Pharmazie

    3 publications · 50 citations

    3

    h-index

1–5