Concepedia

Selective Relaxant Binding Agents

Selective Relaxant Binding Agent is a pharmacological agent that belongs to the class of reversal agents and functions by selectively encapsulating neuromuscular blocking agents through high-affinity binding, thereby rapidly reversing their neuromuscular blockade without directly affecting acetylcholine receptors or acetylcholinesterase activity.

29

Publications

2.5K

Citations

131

Authors

78

Institutions

Publications per year

2017–2026

0

Variants

Srbas

Parents

Publications

29

Reversal of Rocuronium-induced Neuromuscular Block by the Selective Relaxant Binding Agent Sugammadex

Iben Foss Sorgenfrei, K. Norrild, Per Larsen et al. · Anesthesiology · 2006 · 341 citations

, , +17

Reversal of Profound, High-dose Rocuronium-induced Neuromuscular Blockade by Sugammadex at Two Different Time Points: An International, Multicenter, Randomized, Dose-finding, Safety Assessor-blinded, Phase II Trial

F. Pühringer, Christopher Rex, Andreas W. Sielenkämper et al. · Anesthesiology · 2008 · 238 citations

, , +14

Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial

Manfred Blobner, Lars I. Eriksson, Jens Scholz et al. · European Journal of Anaesthesiology · 2010 · 237 citations

, , +14

Effective Reversal of Moderate Rocuronium- or Vecuronium-induced Neuromuscular Block with Sugammadex, a Selective Relaxant Binding Agent

Koen Suy, Karl Morias, Guy Cammu et al. · Anesthesiology · 2007 · 205 citations · Full text

, , +14

A Randomized, Dose-Finding, Phase II Study of the Selective Relaxant Binding Drug, Sugammadex, Capable of Safely Reversing Profound Rocuronium-Induced Neuromuscular Block

Scott B. Groudine, Roy G. Soto, Cynthia A. Lien et al. · Anesthesia & Analgesia · 2007 · 188 citations

, , +12

1–5 of 29

Authors

131

  1. MH
    Marten Heeringa

    Astellas Pharma (Netherlands), Netherlands

    3 publications · 371 citations

    3

    h-index

  2. CC
    Casper Claudius

    Copenhagen University Hospital, Denmark

    3 publications · 426 citations

    3

    h-index

  3. ME
    M. E. Prins

    SNV Netherlands Development Organisation, Netherlands

    3 publications · 816 citations

    3

    h-index

  4. GC
    Guy Cammu

    Onze Lieve Vrouwziekenhuis Hospital, Belgium

    3 publications · 234 citations

    3

    h-index

  5. VD
    Vegard Dahl

    Bærum Sykehus, Norway

    2 publications · 139 citations

    2

    h-index

1–5 of 131

Institutions

78

  1. Copenhagen University Hospital

    Copenhagen, Denmark

    3 h-index

    4 publications

    1.1K citations

  2. SNV Netherlands Development Organisation

    The Hague, Netherlands

    3 h-index

    3 publications

    784 citations

  3. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    3 h-index

    3 publications

    172 citations

  4. Rigshospitalet

    Copenhagen, Denmark

    2 h-index

    3 publications

    831 citations

  5. Innsbruck Medical University

    Innsbruck, Austria

    2 h-index

    2 publications

    414 citations

  6. Radboud University Nijmegen

    Nijmegen, The Netherlands

    2 h-index

    4 publications

    228 citations

  7. Bærum Sykehus

    Drammen, Norway

    2 h-index

    2 publications

    139 citations

  8. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    4 publications

    228 citations

1–8 of 78

Venues

  1. PubMed

    Repository · 4 publications · 76 citations

    4

    h-index

  2. European Journal of Anaesthesiology

    EJA · 3 publications · 354 citations

    3

    h-index

  3. Anesthesiology

    3 publications · 784 citations

    3

    h-index

  4. Anesthesia & Analgesia

    3 publications · 513 citations

    3

    h-index

  5. British Journal of Pharmacology

    BJP · 2 publications · 65 citations

    2

    h-index

1–5