Concepedia

Seipin Function

Seipin Function is a molecular biological mechanism that regulates lipid droplet biogenesis and adipocyte differentiation by ensuring proper lipid homeostasis and membrane curvature during early stages of lipid storage.

112

Publications

10K

Citations

681

Authors

256

Institutions

Publications per year

2017–2026

52

Parents

Publications

112

The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology

Kimberly M. Szymanski, Derk D. Binns, René Bartz et al. · Proceedings of the National Academy of Sciences · 2007 · 622 citations

, , +17

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

Weihua Fei, Guanghou Shui, Bruno Gaëta et al. · The Journal of Cell Biology · 2008 · 473 citations · Full text

, , +17

Seipin is required for converting nascent to mature lipid droplets

Huajin Wang, Michel Becuwe, Benjamin E. Housden et al. · eLife · 2016 · 400 citations · Full text

, , +16

Association of a Homozygous Nonsense Caveolin-1 Mutation with Berardinelli-Seip Congenital Lipodystrophy

Chong Ae Kim, Marc Délepine, Emilie Boutet et al. · The Journal of Clinical Endocrinology & Metabolism · 2008 · 388 citations

, , +17

A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets

Weihua Fei, Guanghou Shui, Yuxi Zhang et al. · PLoS Genetics · 2011 · 359 citations · Full text

, , +16

1–5 of 112

Authors

681

  1. HY
    Hongyuan Yang

    UNSW Sydney, Australia

    15 publications · 2.1K citations

    14

    h-index

  2. JM
    Jocelyne Magré

    Inserm, France

    10 publications · 1.3K citations

    10

    h-index

  3. JJ
    Justin J. Rochford

    University of Cambridge, United Kingdom

    9 publications · 604 citations

    9

    h-index

  4. WC
    Weiqin Chen

    Augusta University, United States

    8 publications · 553 citations

    8

    h-index

  5. JG
    Joel Goodman

    The University of Texas Southwestern Medical Center, United States

    7 publications · 1.3K citations

    7

    h-index

1–5 of 681

Institutions

256

  1. UNSW Sydney

    Sydney, Australia

    14 h-index

    59 publications

    8.7K citations

  2. Sorbonne Université

    Paris, France

    13 h-index

    51 publications

    8.2K citations

  3. Peking University

    Beijing, China

    11 h-index

    65 publications

    2.9K citations

  4. Inserm

    Paris, France

    10 h-index

    82 publications

    9.3K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    48 publications

    4K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    9 h-index

    42 publications

    4.5K citations

  7. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    36 publications

    4.7K citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    9 h-index

    29 publications

    7.4K citations

1–8 of 256

Venues

  1. The Journal of Cell Biology

    JCB · 10 publications · 1.3K citations

    10

    h-index

  2. Diabetes

    5 publications · 437 citations

    5

    h-index

  3. The Plant Cell

    4 publications · 347 citations

    4

    h-index

  4. Developmental Cell

    4 publications · 707 citations

    4

    h-index

  5. Human Molecular Genetics

    4 publications · 346 citations

    4

    h-index

1–5