Concepedia

Secretory Polarization

Secretory Polarization is a cellular mechanism in the context of immune synapse formation whereby the directed trafficking and localized release of secretory vesicles, particularly lytic granules in cytotoxic T cells, becomes spatially reorganized toward the immunological synapse to ensure precise delivery of effector molecules to the target cell.

22

Publications

1.3K

Citations

121

Authors

64

Institutions

Publications per year

2017–2026

2

Parents

Publications

22

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

Gregory D. Rak, Emily M. Mace, Pinaki P. Banerjee et al. · PLoS Biology · 2011 · 233 citations · Full text

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Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function.

Ann E. Cleves, Peter Novick, Vytas A. Bankaitis · The Journal of Cell Biology · 1989 · 232 citations · Full text

, , +17

Linker for Activation of T Cells, ζ-Associated Protein-70, and Src Homology 2 Domain-Containing Leukocyte Protein-76 are Required for TCR-Induced Microtubule-Organizing Center Polarization

Michelle Kuhne, Joseph Lin, Deborah Yablonski et al. · The Journal of Immunology · 2003 · 104 citations · Full text

, , +17

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature

Jiun T. Low, Michael Zavortink, Justin M. Mitchell et al. · Diabetologia · 2014 · 93 citations · Full text

, , +17

Transmissible gastroenteritis virus and porcine epidemic diarrhoea virus infection induces dramatic changes in the tight junctions and microfilaments of polarized IPEC-J2 cells

Shanshan Zhao, Junkai Gao, Liqi Zhu et al. · Virus Research · 2014 · 91 citations · Full text

, , +17

1–5 of 22

Authors

121

  1. SV
    Salvatore Valitutti

    Inserm, France

    4 publications · 152 citations

    4

    h-index

  2. MR
    Magda Rodrigues

    Inserm, France

    2 publications · 97 citations

    2

    h-index

  3. ME
    Michaël Esquerré

    Inserm, France

    2 publications · 94 citations

    2

    h-index

  4. SD
    Sophie Duchez

    Centre National de la Recherche Scientifique, France

    2 publications · 97 citations

    2

    h-index

  5. FB
    Florie Bertrand

    Université Toulouse III - Paul Sabatier, France

    2 publications · 97 citations

    2

    h-index

1–5 of 121

Institutions

64

  1. Inserm

    Paris, France

    4 h-index

    22 publications

    777 citations

  2. Université Toulouse III - Paul Sabatier

    Toulouse, France

    3 h-index

    6 publications

    238 citations

  3. Centre de Physiopathologie de Toulouse-Purpan

    Toulouse, France

    3 h-index

    16 publications

    708 citations

  4. Université Paris Cité

    Paris, France

    2 h-index

    2 publications

    79 citations

  5. University of Illinois Urbana-Champaign

    Urbana, United States

    2 h-index

    4 publications

    717 citations

  6. Délégation Paris 5

    Paris, France

    2 h-index

    2 publications

    79 citations

  7. UK Research and Innovation

    Swindon, United Kingdom

    1 h-index

    1 publications

    46 citations

  8. The University of Sydney

    Sydney, Australia

    1 h-index

    4 publications

    156 citations

1–8 of 64

Venues

  1. The Journal of Immunology

    JI · 4 publications · 219 citations

    4

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 55 citations

    2

    h-index

  3. The Journal of Cell Biology

    JCB · 2 publications · 270 citations

    2

    h-index

  4. Cell and Tissue Research

    2 publications · 52 citations

    2

    h-index

  5. Journal of Extracellular Vesicles

    JEV · 1 publications · 46 citations

    1

    h-index

1–5