Concepedia

Scanning Mutagenesis

Scanning Mutagenesis is a site-directed mutagenesis strategy that systematically introduces mutations at consecutive positions across a target DNA sequence to analyze the functional impact of individual residues in a protein in a comprehensive and ordered manner.

375

Publications

20.7K

Citations

1.6K

Authors

436

Institutions

Publications per year

2017–2026

26

Parents

Publications

375

The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein

Mitchell Garber, Ping Wei, Vineet N. KewalRamani et al. · Genes & Development · 1998 · 431 citations · Full text

, , +16

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

Naveenchandra Suryadevara, Swathi Shrihari, Pavlo Gilchuk et al. · Cell · 2021 · 407 citations · Full text

, , +17

Sequence determinants of amyloid fibril formation

Manuela López de la Paz, Luís Serrano · Proceedings of the National Academy of Sciences · 2003 · 405 citations · Full text

, , +17

<b>Functional analysis of regulatory sequences controlling</b><b>PR‐1 gene expression in Arabidopsis</b>

Edouard G. Lebel, Peter B. Heifetz, Leigh B. Thorne et al. · The Plant Journal · 1998 · 352 citations

, , +17

Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions

Craig S. Gibbs, Mark J. Zoller · Journal of Biological Chemistry · 1991 · 339 citations · Full text

, , +17

1–5 of 375

Authors

1.6K

  1. HR
    H. Ronald Kaback

    University of California, Los Angeles, United States

    14 publications · 531 citations

    14

    h-index

  2. SF
    Stathis Frillingos

    University of Ioannina, Greece

    10 publications · 327 citations

    10

    h-index

  3. TW
    Tip W. Loo

    University of Toronto, Canada

    9 publications · 669 citations

    9

    h-index

  4. DM
    David M. Clarke

    University of Toronto, Canada

    9 publications · 669 citations

    9

    h-index

  5. MM
    Mike Mueckler

    Washington University in St. Louis, United States

    7 publications · 347 citations

    7

    h-index

1–5 of 1.6K

Institutions

436

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    21 h-index

    68 publications

    6.9K citations

  2. University of California, Los Angeles

    Los Angeles, United States

    16 h-index

    52 publications

    2.9K citations

  3. University of Toronto

    Toronto, Canada

    12 h-index

    30 publications

    1.9K citations

  4. Washington University in St. Louis

    St Louis, United States

    11 h-index

    35 publications

    3.7K citations

  5. Yale University

    New Haven, United States

    9 h-index

    25 publications

    1.1K citations

  6. The University of Osaka

    Osaka, Japan

    8 h-index

    29 publications

    1.5K citations

  7. Japan Science and Technology Agency

    Tokyo, Japan

    7 h-index

    15 publications

    655 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    22 publications

    1.3K citations

1–8 of 436

Venues

  1. Journal of Biological Chemistry

    JBC · 117 publications · 6.9K citations

    50

    h-index

  2. Biochemistry

    57 publications · 2.5K citations

    31

    h-index

  3. Journal of Virology

    JVI · 17 publications · 1.6K citations

    17

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1.5K citations

    13

    h-index

  5. Journal of Bacteriology

    JB · 14 publications · 504 citations

    12

    h-index

1–5