Concepedia

Scaffolded Epitope Presentation

Scaffolded Epitope Presentation is a vaccine antigen design strategy in which antigenic epitopes are structurally stabilized and spatially organized through integration onto a protein scaffold to enhance immunogenicity and elicit targeted immune responses.

16

Publications

1.1K

Citations

124

Authors

50

Institutions

Publications per year

2017–2026

4

Parents

Publications

16

Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells

Alexander S. Cheung, David Zhang, Sandeep T. Koshy et al. · Nature Biotechnology · 2018 · 373 citations

, , +12

Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope

Bruno E. Correia, Yih‐En Andrew Ban, Margaret A. Holmes et al. · Structure · 2010 · 224 citations · Full text

, , +17

Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus

Jason S. McLellan, Bruno E. Correia, Man Chen et al. · Journal of Molecular Biology · 2011 · 111 citations

, , +16

Finding a new vaccine in the ricin protein fold

Mark A. Olson, John H. Carra, Virginia Roxas-Duncan et al. · Protein Engineering Design and Selection · 2004 · 74 citations

, , +17

Feasibility of Cowpea chlorotic mottle virus-like particles as scaffold for epitope presentations

A. Hassani‐Mehraban, Sjoerd C.A. Creutzburg, Luc van Heereveld et al. · BMC Biotechnology · 2015 · 40 citations · Full text

, , +17

1–5 of 16

Authors

124

  1. RM
    Rob M. J. Liskamp

    Utrecht University, Netherlands

    3 publications · 74 citations

    3

    h-index

  2. BE
    Bruno E. Correia

    École Polytechnique Fédérale de Lausanne, Switzerland

    3 publications · 370 citations

    3

    h-index

  3. WR
    William R. Schief

    Scripps Research Institute, United States

    2 publications · 335 citations

    2

    h-index

  4. JA
    John A. W. Kruijtzer

    Utrecht University, Netherlands

    2 publications · 47 citations

    2

    h-index

  5. CC
    Cristina Chamorro

    Instituto de Química Médica, Spain

    2 publications · 50 citations

    2

    h-index

1–5 of 124

Institutions

50

  1. Utrecht University

    Utrecht, The Netherlands

    3 h-index

    10 publications

    245 citations

  2. Duke University

    Durham, United States

    2 h-index

    12 publications

    458 citations

  3. Harvard University

    Cambridge, United States

    2 h-index

    8 publications

    1.6K citations

  4. University of Washington

    Seattle, United States

    2 h-index

    9 publications

    1.8K citations

  5. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    1 h-index

    5 publications

    555 citations

  6. United States Military Academy

    West Point, United States

    1 h-index

    1 publications

    23 citations

  7. Institute of Protein Biochemistry

    Naples, Italy

    1 h-index

    3 publications

    96 citations

  8. Heidelberg University

    Heidelberg, Germany

    1 h-index

    2 publications

    54 citations

1–8 of 50

Venues

  1. Vaccine

    2 publications · 59 citations

    2

    h-index

  2. Chemical Communications

    ChemComm · 2 publications · 47 citations

    2

    h-index

  3. Vaccines

    1 publications · 35 citations

    1

    h-index

  4. Journal of Virological Methods

    1 publications · 15 citations

    1

    h-index

  5. ACS Infectious Diseases

    1 publications · 29 citations

    1

    h-index

1–5