Concepedia

Ro52 Autoantigen

Ro52 Autoantigen is a nuclear protein belonging to the family of autoantigens targeted by autoimmune responses in connective tissue disorders, distinguished by its identity as the soluble 52-kDa component of the Ro ribonucleoprotein complex and its association with anti-Ro/SSA antibodies in conditions such as systemic lupus erythematosus and Sjögren’s syndrome.

184

Publications

9.7K

Citations

873

Authors

305

Institutions

Publications per year

2017–2026

26

Variants

Ro52Ssa/ro 52KdaTrim21

Parents

Publications

184

A 52-kD protein is a novel component of the SS-A/Ro antigenic particle.

Eldad Ben‐Chetrit, Edward K. L. Chan, Kevin F. Sullivan et al. · The Journal of Experimental Medicine · 1988 · 403 citations · Full text

, , +17

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

Alexander Espinosa, Valérie Dardalhon, Susanna Brauner et al. · The Journal of Experimental Medicine · 2009 · 306 citations · Full text

, , +17

Short-Term and Long-Term Outcome of Anti-Jo1-Positive Patients with Anti-Ro52 Antibody

I. Marie, P.Y. Hatron, S. Dominique et al. · Seminars in Arthritis and Rheumatism · 2011 · 226 citations

, , +13

Cutting Edge: Autoantigen Ro52 Is an Interferon Inducible E3 Ligase That Ubiquitinates IRF-8 and Enhances Cytokine Expression in Macrophages

Hee Jeong Kong, David E. Anderson, Chang Hoon Lee et al. · The Journal of Immunology · 2007 · 205 citations

, , +17

Anti-Ro52 antibodies frequently co-occur with anti-Jo-1 antibodies in sera from patients with idiopathic inflammatory myopathy

Saskia A. Rutjes, W.T.M. Vree Egberts, P.J.H. Jongen et al. · Clinical & Experimental Immunology · 1997 · 202 citations · Full text

, , +17

1–5 of 184

Authors

873

  1. MW
    Marie Wahren‐Herlenius

    Karolinska Institutet, Sweden

    19 publications · 1.3K citations

    19

    h-index

  2. TP
    Tom P. Gordon

    Flinders Medical Centre, Australia

    11 publications · 431 citations

    11

    h-index

  3. DI
    David Isenberg

    University College London, United Kingdom

    8 publications · 548 citations

    8

    h-index

  4. LO
    Lars Ottosson

    Karolinska Institutet, Sweden

    7 publications · 432 citations

    7

    h-index

  5. MS
    Maria Sunnerhagen

    Linköping University, Sweden

    7 publications · 410 citations

    7

    h-index

1–5 of 873

Institutions

305

  1. Karolinska Institutet

    Stockholm, Sweden

    21 h-index

    107 publications

    9K citations

  2. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    16 h-index

    78 publications

    4.8K citations

  3. Flinders Medical Centre

    Bedford Park, Australia

    12 h-index

    32 publications

    1.1K citations

  4. Radboud University Nijmegen

    Nijmegen, The Netherlands

    12 h-index

    28 publications

    1.3K citations

  5. University of Oklahoma Health Sciences Center

    Oklahoma City, United States

    9 h-index

    25 publications

    1.1K citations

  6. Harvard University

    Cambridge, United States

    9 h-index

    21 publications

    2.2K citations

  7. University College London

    London, United Kingdom

    9 h-index

    19 publications

    1.1K citations

  8. Karolinska University Hospital

    Stockholm, Sweden

    7 h-index

    25 publications

    1.5K citations

1–8 of 305

Venues

  1. PubMed

    Repository · 18 publications · 700 citations

    17

    h-index

  2. Clinical & Experimental Immunology

    CEI · 15 publications · 809 citations

    14

    h-index

  3. Arthritis & Rheumatism

    11 publications · 818 citations

    11

    h-index

  4. Journal of Autoimmunity

    10 publications · 346 citations

    10

    h-index

  5. Lupus

    7 publications · 255 citations

    7

    h-index

1–5