Risk stratification is the systematic categorization of individuals or populations into distinct levels of likelihood for developing or experiencing a specific adverse health outcome based on clinical, demographic, genetic, or behavioral indicators, enabling targeted intervention and resource allocation across diverse domains such as cancer screening, cardiac nuclear medicine, clinical decision support, diabetic foot care, early detection, health data analytics, nursing data analytics, patient safety informatics, perioperative outcomes research, population health analytics, population health informatics, population health management, population health nursing, and precision medicine.