Concepedia

Ribosomal Proofreading

Ribosomal Proofreading is a biochemical mechanism within the broader process of translational fidelity whereby the ribosome discriminates against incorrect aminoacyl-tRNAs during codon recognition by exploiting kinetic delays to enhance the accuracy of protein synthesis.

81

Publications

6.9K

Citations

250

Authors

128

Institutions

Publications per year

2017–2026

14

Variants

Ribosome Proofreading

Parents

Publications

81

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

Marina Manuvakhova, Kim M. Keeling, David M. Bedwell · RNA · 2000 · 403 citations

, , +17

Misreading of RNA Codewords Induced by Aminoglycoside Antibiotics

Julian Davies, Luigi Gorini, Bernard D. Davis · Molecular Pharmacology · 1965 · 400 citations

, , +16

Kinetic Determinants of High-Fidelity tRNA Discrimination on the Ribosome

Kirill B. Gromadski, Marina V. Rodnina · Molecular Cell · 2004 · 373 citations · Full text

, , +14

Induced fit in initial selection and proofreading of aminoacyl‐tRNA on the ribosome

Tillmann Pape, Wolfgang Wintermeyer, Marina V. Rodnina · The EMBO Journal · 1999 · 331 citations · Full text

, , +12

Compensatory adaptation to the deleterious effect of antibiotic resistance in <i>Salmonella typhimurium</i>

Sophie Maisnier‐Patin, Otto G. Berg, Lars Liljas et al. · Molecular Microbiology · 2002 · 236 citations · Full text

, , +17

1–5 of 81

Authors

250

  1. RT
    Richard Thompson

    Juvenile Protective Association, United States

    7 publications · 536 citations

    7

    h-index

  2. DB
    Daniel B. Dix

    University of Colorado Boulder, United States

    7 publications · 392 citations

    7

    h-index

  3. ME
    Måns Ehrenberg

    Uppsala University, Sweden

    5 publications · 515 citations

    5

    h-index

  4. CG
    C. G. Kurland

    Uppsala University, Sweden

    4 publications · 446 citations

    4

    h-index

  5. AM
    Amr M. Karim

    Ain Shams University, Egypt

    3 publications · 212 citations

    3

    h-index

1–5 of 250

Institutions

128

  1. Uppsala University

    Uppsala, Sweden

    8 h-index

    21 publications

    1.7K citations

  2. University of Colorado Boulder

    Boulder, United States

    7 h-index

    18 publications

    935 citations

  3. Harvard University

    Cambridge, United States

    5 h-index

    9 publications

    1.9K citations

  4. Max Planck Society

    Munich, Germany

    3 h-index

    3 publications

    870 citations

  5. The Ohio State University

    Columbus, United States

    3 h-index

    9 publications

    339 citations

  6. Institute for Advanced Study

    Princeton, United States

    3 h-index

    5 publications

    532 citations

  7. Heidelberg University

    Heidelberg, Germany

    3 h-index

    11 publications

    1.2K citations

  8. Center for Systems Biology

    Boston, United States

    3 h-index

    6 publications

    602 citations

1–8 of 128

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 987 citations

    11

    h-index

  2. Journal of Molecular Biology

    JMB · 7 publications · 441 citations

    7

    h-index

  3. Nucleic Acids Research

    7 publications · 593 citations

    7

    h-index

  4. RNA

    6 publications · 633 citations

    6

    h-index

  5. Journal of Biological Chemistry

    JBC · 5 publications · 266 citations

    5

    h-index

1–5