Concepedia

Restriction Enzyme Engineering

Restriction Enzyme Engineering is a methodological framework within molecular biotechnology that involves the rational design and modification of restriction enzymes to alter their sequence specificity, catalytic efficiency, or structural stability for targeted DNA manipulation applications.

138

Publications

9.3K

Citations

447

Authors

143

Institutions

Publications per year

2017–2026

6

Parents

Publications

138

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

Joachim Messing, Jeffrey Vieira · Gene · 1982 · 2.9K citations

, , +9

McrA and McrB restriction phenotypes of some<i>E.coli</i>strains and implications for gene cloning

Elisabeth A. Raleigh, Noreen E. Murray, Helen R. Revel et al. · Nucleic Acids Research · 1988 · 341 citations · Full text

, , +15

Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression

Tamar Unger, Yossi Jacobovitch, Ada Dantes et al. · Journal of Structural Biology · 2010 · 261 citations

, , +16

A general method for maximizing the expression of a cloned gene.

Thomas M. Roberts, R Kacich, Mark Ptashne · Proceedings of the National Academy of Sciences · 1979 · 173 citations · Full text

, , +17

Cloning of the YenI restriction endonuclease and methyltransferase from Yersinia enterocolitica serotype O8 and construction of a transformable R−M+ mutant

Susan A. Kinder, Julie L. Badger, Gene O. Bryant et al. · Gene · 1993 · 172 citations

, , +12

1–5 of 138

Authors

447

  1. AP
    Alfred Pingoud

    Justus-Liebig-Universität Gießen, Germany

    8 publications · 221 citations

    8

    h-index

  2. SB
    Sierd Bron

    University of Groningen, Netherlands

    5 publications · 391 citations

    5

    h-index

  3. WS
    Waclaw Szybalski

    University of Wisconsin–Madison, United States

    4 publications · 142 citations

    4

    h-index

  4. TL
    Thomas Lanio

    Justus-Liebig-Universität Gießen, Germany

    4 publications · 141 citations

    4

    h-index

  5. TA
    Thomas A. Trautner

    Max Planck Institute for Molecular Genetics, Germany

    4 publications · 307 citations

    4

    h-index

1–5 of 447

Institutions

143

  1. New England Biolabs (United States)

    Ipswich, United States

    13 h-index

    48 publications

    2.2K citations

  2. Justus-Liebig-Universität Gießen

    Giessen, Germany

    8 h-index

    28 publications

    783 citations

  3. University of Edinburgh

    Edinburgh, United Kingdom

    6 h-index

    10 publications

    832 citations

  4. Max Planck Institute for Molecular Genetics

    Berlin, Germany

    5 h-index

    8 publications

    480 citations

  5. Johns Hopkins Medicine

    Baltimore, United States

    4 h-index

    9 publications

    685 citations

  6. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    10 publications

    255 citations

  7. University of Groningen

    Groningen, The Netherlands

    4 h-index

    7 publications

    409 citations

  8. Johns Hopkins University

    Baltimore, United States

    4 h-index

    12 publications

    802 citations

1–8 of 143

Venues

  1. Molecular and General Genetics MGG

    19 publications · 812 citations

    16

    h-index

  2. Nucleic Acids Research

    17 publications · 940 citations

    15

    h-index

  3. Gene

    15 publications · 3.6K citations

    14

    h-index

  4. Journal of Molecular Biology

    JMB · 10 publications · 483 citations

    10

    h-index

  5. Journal of Biological Chemistry

    JBC · 6 publications · 402 citations

    6

    h-index

1–5